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Cruises from Southampton to Italy

Find the best cruise to Italy from Southampton for you in 2026, 2027 and 2028 with Stewart Travel below. Call one of our Cruise Experts on 0800 917 5742 to book your dream cruise holiday today!

Italian Cruises from Southampton

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    Eastern Mediterranean Discovery

    P&O Cruises

    Ventura 26 February 2027 21 nights

    Itinerary: Southampton - Cartagena - La Goulette - Malta - Athens - Naples - Rome - Barcelona - Alicante - Cadiz...

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask About Exclusive 10% Past Passenger Discount
    • No Tipping Required

    Sail From UK from

    • Interior £1,629pp
    • Ocean View £1,679pp
    • Balcony £2,069pp

    Includes extra savings of up to £72pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 29 March 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Corsica - Southampton

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,369pp
    • Ocean View £1,519pp
    • Balcony £1,519pp
    • Suite £1,889pp

    Includes extra savings of up to £59pp

    more details

    Culture & Coastline of Italy

    Fred Olsen Cruise Lines

    Small Ship Experience

    Balmoral 02 April 2027 18 nights

    Itinerary: Southampton - Cadiz - Florence/Pisa - Rome - Olbia/Sardinia - Alghero - Mahon - Southampton

    • Wine, Beer & Soft Drinks Included with Lunch & Dinner - When Booking Freedom Fare
    • Gratuities Included
    • Upgrade to Premium Drinks from £40pp per day
    • Features Fred. Olsen Signature Experiences - Scenic Discoveries, Itinerary Insights & Destination Inspired Menus

    Sail From UK from

    • Interior £2,639pp
    • Ocean View £3,229pp
    • Balcony Call Us

    Includes extra savings of up to £66pp

    more details

    Mediterranean and Greek Islands

    Cunard

    Queen Elizabeth 02 May 2027 26 nights

    Itinerary: Southampton - La Coruna - Leixoes - Gibraltar - Tangier - Cartagena - Alicante - Majorca - Barcelona - Sicily...

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details
    • FREE up to $600 On Board Spend

    Sail From UK from

    • Interior £2,639pp
    • Ocean View £2,979pp
    • Balcony £3,609pp
    • Suite Call Us

    Includes extra savings of up to £78pp

    more details

    Mediterranean, Greek Islands and Adriatic

    Cunard

    Queen Elizabeth 02 May 2027 33 nights

    Itinerary: Southampton - La Coruna - Leixoes - Gibraltar - Tangier - Cartagena - Alicante - Majorca - Barcelona - Sicily...

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details
    • FREE up to $600 On Board Spend

    Sail From UK from

    • Interior £3,609pp
    • Ocean View £3,869pp
    • Balcony £5,009pp
    • Suite £11,419pp

    Includes extra savings of up to £237pp

    more details

    Mediterranean, Greek Islands and Adriatic

    Cunard

    Queen Elizabeth 02 May 2027 40 nights

    Itinerary: Southampton - La Coruna - Leixoes - Gibraltar - Tangier - Cartagena - Alicante - Majorca - Barcelona - Sicily...

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details
    • FREE up to $600 On Board Spend

    Sail From UK from

    • Interior £4,109pp
    • Ocean View £4,309pp
    • Balcony Call Us
    • Suite £10,529pp

    Includes extra savings of up to £219pp

    more details

    Spain and Portugal

    Cunard

    Queen Victoria 04 May 2027 24 nights

    Itinerary: Southampton - Lisbon - Cadiz - Alicante - Valencia - Majorca - Barcelona - Athens - Istanbul - Kusadasi...

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details
    • FREE up to $600 On Board Spend

    Sail From UK from

    Call us now on 0800 917 5742

    more details

    Mediterranean - Spain France and Italy

    P&O Cruises

    Arvia 09 May 2027 14 nights

    Itinerary: Southampton - Cadiz - Malaga - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask About Exclusive 10% Past Passenger Discount
    • No Tipping Required

    Sail From UK from

    • Interior £1,079pp
    • Ocean View £1,559pp
    • Balcony £1,929pp

    Includes extra savings of up to £27pp

    more details

    Italy, Spain and Portugal

    Cunard

    Queen Anne 09 May 2027 18 nights

    Itinerary: Southampton - Lisbon - Alicante - Barcelona - Rome - Naples - Sicily - Cagliari - Malaga - Cadiz...

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details
    • FREE up to $600 On Board Spend
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,759pp
    • Ocean View £2,429pp
    • Balcony £2,449pp
    • Suite £5,159pp

    Includes extra savings of up to £105pp

    more details

    Mediterranean - Spain France and Italy

    P&O Cruises

    Arvia 06 June 2027 14 nights

    Itinerary: Southampton - Cadiz - Malaga - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask About Exclusive 10% Past Passenger Discount
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,179pp
    • Ocean View £1,779pp
    • Balcony £1,979pp

    Includes extra savings of up to £30pp

    more details

    Mediterranean - Spain France and Italy

    P&O Cruises

    Arvia 04 July 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask About Exclusive 10% Past Passenger Discount
    • No Tipping Required

    Sail From UK from

    • Interior £1,379pp
    • Ocean View £1,859pp
    • Balcony £2,069pp

    Includes extra savings of up to £31pp

    more details

    London (Southampton) to Athens (Piraeus)

    Regent Seven Seas Cruises

    Luxury

    Seven Seas Mariner 30 July 2027 82 nights

    Itinerary: Southampton - Honfleur - St. Peter Port - St Malo - La Rochelle - Bordeaux - Biarritz - Bilbao - Santiago de Compostela - Lisbon...

    • Unlimited Beverages
    • Gratuities
    • Unlimited Shore Excursions

    Sail From UK from

    • Suite £54,529pp

    Includes extra savings of up to £2,870pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 07 August 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Alghero - Southampton

    • Top Deal
    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities
    • FREE up to $500 On Board Spend
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,609pp
    • Ocean View £1,999pp
    • Balcony £1,999pp
    • Suite £2,389pp

    Includes extra savings of up to £74pp

    more details

    Mediterranean - Spain France and Italy

    P&O Cruises

    Arvia 15 August 2027 14 nights

    Itinerary: Southampton - Cadiz - Malaga - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask About Exclusive 10% Past Passenger Discount
    • No Tipping Required

    Sail From UK from

    • Interior £1,659pp
    • Ocean View Call Us
    • Balcony £3,009pp

    more details

    Southampton to Civitavecchia (Rome)

    Silversea

    Luxury

    Silver Spirit 25 August 2027 21 nights

    Itinerary: Southampton - Honfleur - St Malo - Bordeaux - Vigo - Leixoes - Lisbon - Portimao - Cadiz - Malaga...

    • Unlimited Beverages
    • Gratuities

    Sail From UK from

    Call us now on 0800 917 5742

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 28 August 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Alghero - Southampton

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities
    • FREE up to $500 On Board Spend
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,469pp
    • Ocean View £2,229pp
    • Balcony £2,119pp
    • Suite £2,399pp

    more details

    Mediterranean and Morocco Discovery

    P&O Cruises

    Arcadia 01 September 2027 19 nights

    Itinerary: Southampton - Lisbon - Alicante - Florence/Pisa - Rome - Cartagena - Casablanca - Tangier - Vigo - Southampton

    • Adult Only
    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask About Exclusive 10% Past Passenger Discount
    • No Tipping Required

    Sail From UK from

    • Interior £1,979pp
    • Ocean View £2,049pp
    • Balcony £2,919pp

    Includes extra savings of up to £47pp

    more details

    14 Night Best Of Italy, Spain & France

    Celebrity Cruises

    Luxury

    Celebrity Apex 11 September 2027 14 nights

    Itinerary: Southampton - Gibraltar - Cagliari - Rome - Florence/Pisa - Cannes - Barcelona - Cadiz - Southampton

    • Exclusive Offer - Incredible Savings, Drinks & WiFi Included

    Sail From UK from

    • Interior £2,949pp
    • Ocean View £3,099pp
    • Balcony £3,799pp
    • Suite Call Us

    Exclusive Savings of up to £1549 per couple

    more details

    London to Istanbul

    Oceania Cruises

    Luxury

    Marina 11 September 2027 47 nights

    Itinerary: Southampton - Zeebrugge - Rotterdam - IJmuiden (for Amsterdam) - Newcastle - Newhaven - Hamburg - Paris - La Rochelle - Le Verdon...

    • Gratuities
    • Gourmet Speciality Dining
    • Soft Drinks, Bottled Water, Speciality Tea & Coffee
    • Unlimited WiFi
    • In Suite & In Stateroom Dining

    Sail From UK from

    Call us now on 0800 917 5742

    more details

    Mediterranean - Spain France and Italy

    P&O Cruises

    Arvia 12 September 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask About Exclusive 10% Past Passenger Discount
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,479pp
    • Ocean View £2,119pp
    • Balcony £2,319pp

    Includes extra savings of up to £36pp

    more details

    Mediterranean Marvel

    Princess Cruises

    Sky Princess 25 September 2027 31 nights

    Itinerary: Southampton - Guernsey - Seville - Malaga - Cartagena - Barcelona - Toulon - Florence/Pisa - Rome - Naples...

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities

    Sail From UK from

    • Interior £3,479pp
    • Ocean View £5,499pp
    • Balcony £5,219pp
    • Suite £7,209pp

    Includes extra savings of up to £223pp

    more details

    Ultimate Mediterranean Grand Adventure

    Princess Cruises

    Sky Princess 25 September 2027 46 nights

    Itinerary: Southampton - Guernsey - Seville - Malaga - Cartagena - Barcelona - Toulon - Florence/Pisa - Rome - Naples...

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities

    Sail From UK from

    • Interior £4,169pp
    • Ocean View £6,439pp
    • Balcony £6,159pp
    • Suite Call Us

    Includes extra savings of up to £199pp

    more details

    Icons of the Mediterranean

    Fred Olsen Cruise Lines

    Small Ship Experience

    Bolette 18 November 2027 16 nights

    Itinerary: Southampton - Gibraltar - Barcelona - Ajaccio - Rome - Florence/Pisa - Cartagena - Lisbon - Southampton

    • Wine, Beer & Soft Drinks Included with Lunch & Dinner - When Booking Freedom Fare
    • Gratuities Included
    • Upgrade to Premium Drinks from £40pp per day
    • Features Fred. Olsen Signature Experiences - Scenic Discoveries, Itinerary Insights & Destination Inspired Menus

    Sail From UK from

    • Interior £1,759pp
    • Ocean View £2,289pp
    • Balcony £3,279pp

    Includes extra savings of up to £79pp

    more details

    Spain and Italy

    Cunard

    Queen Mary 2 31 March 2028 14 nights

    Itinerary: Southampton - Vigo - Barcelona - Rome - Alghero - Malaga - Cadiz - Southampton

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details
    • FREE up to $600 On Board Spend
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,939pp
    • Ocean View £2,639pp
    • Balcony £2,819pp
    • Suite £5,879pp

    Includes extra savings of up to £120pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 22 April 2028 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Corsica - Southampton

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,449pp
    • Ocean View £1,839pp
    • Balcony £1,759pp
    • Suite £2,349pp

    Includes extra savings of up to £73pp

    more details

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