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Cruises from Southampton to Italy

Find the best cruise to Italy from Southampton for you in 2026, 2027 and 2028 with Stewart Travel below. Call one of our Cruise Experts on 0800 019 0063 to book your dream cruise holiday today!

Italian Cruises from Southampton

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    London to Istanbul

    Oceania Cruises

    Luxury

    Sirena 05 August 2026 22 nights

    Itinerary: Southampton - Le Verdon - Biarritz - Santander - Ferrol - Porto - Lisbon - Cadiz - Malaga - Almeria...

    • Gratuities
    • Gourmet Speciality Dining
    • Soft Drinks, Bottled Water, Speciality Tea & Coffee
    • Unlimited WiFi
    • In Suite & In Stateroom Dining

    Sail From UK from

    • Interior Call Us
    • Ocean View Call Us
    • Balcony £9,139pp
    • Suite £11,209pp

    Includes extra savings of up to £590pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 30 August 2026 14 nights

    Itinerary: Southampton - Seville - Barcelona - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    Italy, France and Spain

    Cunard

    Queen Anne 06 September 2026 14 nights

    Itinerary: Southampton - Cartagena - Rome - Florence/Pisa - Marseille - Malaga - Gibraltar - Southampton

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,469pp
    • Ocean View £2,649pp
    • Balcony £2,829pp
    • Suite £4,499pp

    more details

    Spain and Italy

    Cunard

    Queen Anne 06 September 2026 6 nights

    Itinerary: Southampton - Cartagena - Rome

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    14 Night Best Of Italy, Spain & France

    Celebrity Cruises

    Luxury

    Celebrity Apex 12 September 2026 14 nights

    Itinerary: Southampton - Cadiz - Cagliari - Rome - Florence/Pisa - Nice (Villefranche) - Barcelona - La Coruna - Southampton

    • Ask about adding Drinks & WiFi

    Sail From UK from

    • Interior £2,309pp
    • Ocean View £2,789pp
    • Balcony £2,709pp
    • Suite £13,989pp

    more details

    Eastern Mediterranean Discovery

    P&O Cruises

    Ventura 26 February 2027 21 nights

    Itinerary: Southampton - Cartagena - La Goulette - Malta - Athens - Naples - Rome - Barcelona - Alicante - Cadiz...

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    • Interior £1,479pp
    • Ocean View £1,729pp
    • Balcony £2,069pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 29 March 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Corsica - Southampton

    • Includes Savings of up to £750
    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities

    Sail From UK from

    • Interior £1,199pp
    • Ocean View £1,449pp
    • Balcony £1,299pp
    • Suite £1,669pp

    more details

    Culture & Coastline of Italy

    Fred Olsen Cruise Lines

    Small Ship Experience

    Balmoral 02 April 2027 18 nights

    Itinerary: Southampton - Cadiz - Florence/Pisa - Rome - Olbia/Sardinia - Alghero - Mahon - Southampton

    • Wine, Beer & Soft Drinks Included with Lunch & Dinner - When Booking Freedom Fare
    • Gratuities Included
    • Upgrade to Premium Drinks from £40pp per day
    • Features Fred. Olsen Signature Experiences - Scenic Discoveries, Itinerary Insights & Destination Inspired Menus

    Sail From UK from

    • Interior £2,349pp
    • Ocean View £2,839pp
    • Balcony £5,579pp

    Includes extra savings of up to £120pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 25 April 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    Mediterranean and Greek Islands

    Cunard

    Queen Elizabeth 02 May 2027 26 nights

    Itinerary: Southampton - La Coruna - Leixoes - Tangier - Gibraltar - Cartagena - Alicante - Valencia - Barcelona - Sicily...

    • Includes Savings of up to £200 on Balcony cabins
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £2,449pp
    • Ocean View £2,789pp
    • Balcony £3,079pp
    • Suite £6,899pp

    more details

    Mediterranean, Greek Islands and Adriatic

    Cunard

    Queen Elizabeth 02 May 2027 33 nights

    Itinerary: Southampton - La Coruna - Leixoes - Tangier - Gibraltar - Cartagena - Alicante - Valencia - Barcelona - Sicily...

    • Includes Savings of up to £200 on Balcony cabins
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £3,279pp
    • Ocean View £3,519pp
    • Balcony £4,109pp
    • Suite £9,319pp

    more details

    Mediterranean, Greek Islands and Adriatic

    Cunard

    Queen Elizabeth 02 May 2027 40 nights

    Itinerary: Southampton - La Coruna - Leixoes - Tangier - Gibraltar - Cartagena - Alicante - Valencia - Barcelona - Sicily...

    • Includes Savings of up to £200 on Balcony cabins
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £3,899pp
    • Ocean View Call Us
    • Balcony Call Us
    • Suite £10,529pp

    more details

    Spain and Portugal

    Cunard

    Queen Victoria 04 May 2027 24 nights

    Itinerary: Southampton - Lisbon - Cadiz - Alicante - Valencia - Majorca - Barcelona - Athens - Istanbul - Kusadasi...

    • Includes Savings of up to £200 on Balcony cabins
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 09 May 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask about FREE Kids Places
    • No Tipping Required

    Sail From UK from

    • Interior £1,229pp
    • Ocean View £1,779pp
    • Balcony £2,119pp

    more details

    Italy, Spain and Portugal

    Cunard

    Queen Anne 09 May 2027 18 nights

    Itinerary: Southampton - Lisbon - Alicante - Barcelona - Rome - Naples - Sicily - Cagliari - Malaga - Cadiz...

    • Includes Savings of up to £200 on Balcony cabins
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £1,609pp
    • Ocean View £2,199pp
    • Balcony £2,589pp
    • Suite £5,749pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 06 June 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask about FREE Kids Places
    • No Tipping Required

    Sail From UK from

    • Interior £1,229pp
    • Ocean View £1,679pp
    • Balcony £1,979pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 04 July 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask about Reduced Kids Places
    • No Tipping Required

    Sail From UK from

    • Interior £1,229pp
    • Ocean View £1,729pp
    • Balcony £2,019pp

    more details

    London (Southampton) to Athens (Piraeus)

    Regent Seven Seas Cruises

    Luxury

    Seven Seas Mariner 30 July 2027 82 nights

    Itinerary: Southampton - Honfleur - St. Peter Port - St Malo - La Rochelle - Bordeaux - Biarritz - Bilbao - Santiago de Compostela - Lisbon...

    • Unlimited Beverages
    • Gratuities
    • Unlimited Shore Excursions

    Sail From UK from

    • Suite £51,059pp

    Includes extra savings of up to £2,687pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 07 August 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Alghero - Southampton

    • Top Deal
    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities

    Sail From UK from

    • Interior £1,299pp
    • Ocean View £1,679pp
    • Balcony £1,519pp
    • Suite £1,759pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 15 August 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask about Reduced Kids Places
    • No Tipping Required

    Sail From UK from

    • Interior £1,629pp
    • Ocean View Call Us
    • Balcony £2,519pp

    more details

    Southampton to Civitavecchia (Rome)

    Silversea

    Luxury

    Silver Spirit 25 August 2027 21 nights

    Itinerary: Southampton - Honfleur - St Malo - Bordeaux - Vigo - Leixoes - Lisbon - Portimao - Cadiz - Malaga...

    • Unlimited Beverages
    • Gratuities

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 28 August 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Alghero - Southampton

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities

    Sail From UK from

    • Interior £1,179pp
    • Ocean View £1,639pp
    • Balcony £1,479pp
    • Suite £1,659pp

    more details

    Mediterranean And Morocco Discovery

    P&O Cruises

    Arcadia 01 September 2027 19 nights

    Itinerary: Southampton - Lisbon - Alicante - Florence/Pisa - Rome - Majorca - Casablanca - Tangier - Vigo - Southampton

    • Adult Only
    • Upgrade to the New All Inclusive Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Ask about FREE Kids Places
    • No Tipping Required

    Sail From UK from

    • Interior £1,829pp
    • Ocean View £1,929pp
    • Balcony £2,569pp

    more details

    14 Night Best Of Italy, Spain & France

    Celebrity Cruises

    Luxury

    Celebrity Apex 11 September 2027 14 nights

    Itinerary: Southampton - Gibraltar - Cagliari - Rome - Florence/Pisa - Cannes - Barcelona - Cadiz - Southampton

    • Exclusive Offer - Incredible Savings, Drinks & WiFi Included

    Sail From UK from

    • Interior £2,869pp
    • Ocean View £3,049pp
    • Balcony £3,299pp
    • Suite Call Us

    Exclusive Savings of up to £1549 per couple

    more details

    London to Istanbul

    Oceania Cruises

    Luxury

    Marina 11 September 2027 47 nights

    Itinerary: Southampton - Zeebrugge - Rotterdam - IJmuiden (for Amsterdam) - Newcastle - Newhaven - Hamburg - Paris - La Rochelle - Le Verdon...

    • Gratuities
    • Gourmet Speciality Dining
    • Soft Drinks, Bottled Water, Speciality Tea & Coffee
    • Unlimited WiFi
    • In Suite & In Stateroom Dining

    Sail From UK from

    • Interior £11,289pp
    • Ocean View Call Us
    • Balcony £16,099pp
    • Suite £22,689pp

    Includes extra savings of up to £1,194pp

    more details

    • Next

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    What our clients say

    Platinum Service Award Winners

    Average Customer Rating: 4.9/5

    Excellent service. Very patient

    Mrs Snell / July 2026

    You always come out with a lighter step in your shoes

    Firstly the Psisley staff are bright and cheerful. They listen to you and seem to get ghe holiday you need.

    Mrs Duffy / July 2026

    Happy customer.

    Very pleasant and efficient personell. Even got offered a coffee.????

    Trusted Customer / July 2026

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