Call free 0800 019 0063 We are open today between 9am and 4:30pm

Home / Fly Cruises / P&O Cruises / To Mediterranean

P&O Fly Cruises to the Mediterranean

Find the best P&O fly cruise to the Mediterranean for you in 2026, 2027 and 2028 with Stewart Travel below. Call one of our Cruise Experts on 0800 019 0063 to book your dream fly cruise holiday today!

P&O Fly Mediterranean Cruises

×

Filter Results

    • Next

    Western Mediterranean

    P&O Cruises

    Azura 02 April 2026 7 nights

    Itinerary: Malta - Toulon - Florence/Pisa - Rome - Naples - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £939pp
    • Ocean View £1,029pp
    • Balcony £989pp

    Includes extra savings of up to £16pp

    more details

    Mediterranean

    P&O Cruises

    Azura 02 April 2026 14 nights

    Itinerary: Malta - Toulon - Florence/Pisa - Rome - Naples - Malta - Split - Zadar - Dubrovnik - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,429pp
    • Ocean View £1,529pp
    • Balcony £1,559pp

    Includes extra savings of up to £16pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 09 April 2026 7 nights

    Itinerary: Malta - Split - Zadar - Dubrovnik - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £889pp
    • Ocean View £1,009pp
    • Balcony £1,059pp

    Includes extra savings of up to £15pp

    more details

    Mediterranean

    P&O Cruises

    Azura 09 April 2026 14 nights

    Itinerary: Malta - Split - Zadar - Dubrovnik - Malta - Athens - Chania - Olympie - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,629pp
    • Ocean View £1,579pp
    • Balcony £1,859pp

    Includes extra savings of up to £19pp

    more details

    Greek Islands

    P&O Cruises

    Azura 16 April 2026 7 nights

    Itinerary: Malta - Athens - Chania - Olympie - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £819pp
    • Ocean View £889pp
    • Balcony £989pp

    Includes extra savings of up to £10pp

    more details

    Mediterranean

    P&O Cruises

    Azura 16 April 2026 14 nights

    Itinerary: Malta - Athens - Chania - Olympie - Malta - Toulon - Florence/Pisa - Rome - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,209pp
    • Ocean View £1,429pp
    • Balcony £1,479pp

    Includes extra savings of up to £27pp

    more details

    Western Mediterranean

    P&O Cruises

    Azura 23 April 2026 7 nights

    Itinerary: Malta - Toulon - Florence/Pisa - Rome - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £689pp
    • Ocean View £719pp
    • Balcony £789pp

    Includes extra savings of up to £15pp

    more details

    Mediterranean

    P&O Cruises

    Azura 23 April 2026 14 nights

    Itinerary: Malta - Toulon - Florence/Pisa - Rome - Malta - Corfu - Dubrovnik - Zadar - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,279pp
    • Ocean View £1,729pp
    • Balcony £1,879pp

    Includes extra savings of up to £34pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 30 April 2026 7 nights

    Itinerary: Malta - Corfu - Dubrovnik - Zadar - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £919pp
    • Ocean View £1,049pp
    • Balcony £1,329pp

    Includes extra savings of up to £13pp

    more details

    Mediterranean

    P&O Cruises

    Azura 30 April 2026 14 nights

    Itinerary: Malta - Corfu - Dubrovnik - Zadar - Catania - Malta - Santorini - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,479pp
    • Ocean View £2,189pp
    • Balcony £2,269pp

    Includes extra savings of up to £34pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 04 June 2026 7 nights

    Itinerary: Malta - Catania - Dubrovnik - Corfu - Taranto - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,179pp
    • Ocean View £1,379pp
    • Balcony £1,729pp

    Includes extra savings of up to £22pp

    more details

    Mediterranean

    P&O Cruises

    Azura 04 June 2026 14 nights

    Itinerary: Malta - Catania - Dubrovnik - Corfu - Taranto - Malta - Santorini - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £2,089pp
    • Ocean View £2,279pp
    • Balcony Call Us

    Includes extra savings of up to £23pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 11 June 2026 7 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £59pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,159pp
    • Ocean View £1,209pp
    • Balcony £1,499pp

    Includes extra savings of up to £36pp

    more details

    Mediterranean

    P&O Cruises

    Azura 11 June 2026 14 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta - Taranto - Corfu - Kefalonia - Catania...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £85pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,679pp
    • Ocean View £1,829pp
    • Balcony £2,569pp

    Includes extra savings of up to £38pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 18 June 2026 7 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £59pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,169pp
    • Ocean View £1,209pp
    • Balcony £1,369pp

    Includes extra savings of up to £18pp

    more details

    Mediterranean

    P&O Cruises

    Azura 18 June 2026 14 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta - Calvi - Florence/Pisa - Rome - Naples...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £84pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,699pp
    • Ocean View £1,659pp
    • Balcony £2,069pp

    Includes extra savings of up to £38pp

    more details

    Western Mediterranean

    P&O Cruises

    Azura 25 June 2026 7 nights

    Itinerary: Malta - Calvi - Florence/Pisa - Rome - Naples - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £50pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £989pp
    • Ocean View £1,029pp
    • Balcony £1,259pp

    Includes extra savings of up to £17pp

    more details

    Mediterranean

    P&O Cruises

    Azura 25 June 2026 14 nights

    Itinerary: Malta - Calvi - Florence/Pisa - Rome - Naples - Malta - Mykonos - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £85pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,679pp
    • Ocean View £1,719pp
    • Balcony £2,279pp

    Includes extra savings of up to £34pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 02 July 2026 7 nights

    Itinerary: Malta - Mykonos - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £60pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,189pp
    • Ocean View £1,239pp
    • Balcony £1,409pp

    Includes extra savings of up to £20pp

    more details

    Mediterranean

    P&O Cruises

    Azura 02 July 2026 14 nights

    Itinerary: Malta - Mykonos - Rhodes - Ephesus - Athens - Malta - Taranto - Corfu - Kefalonia - Catania...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £84pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,659pp
    • Ocean View £1,849pp
    • Balcony £2,519pp

    Includes extra savings of up to £41pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 09 July 2026 7 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Top Deal
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £51pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,009pp
    • Ocean View £1,009pp
    • Balcony £1,259pp

    Includes extra savings of up to £20pp

    more details

    Mediterranean

    P&O Cruises

    Azura 09 July 2026 14 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta - Chania - Athens - Mykonos - Heraklion...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £85pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,699pp
    • Ocean View £1,689pp
    • Balcony £2,299pp

    Includes extra savings of up to £30pp

    more details

    Greek Islands

    P&O Cruises

    Azura 16 July 2026 7 nights

    Itinerary: Malta - Chania - Athens - Mykonos - Heraklion - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £46pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £919pp
    • Ocean View £939pp
    • Balcony £1,099pp

    Includes extra savings of up to £20pp

    more details

    Mediterranean

    P&O Cruises

    Azura 16 July 2026 14 nights

    Itinerary: Malta - Chania - Athens - Mykonos - Heraklion - Malta - Corfu - Kotor - Split - Dubrovnik...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £87pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,729pp
    • Ocean View £1,919pp
    • Balcony £2,349pp

    Includes extra savings of up to £24pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 23 July 2026 7 nights

    Itinerary: Malta - Corfu - Kotor - Split - Dubrovnik - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £65pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • Additional Savings of up to £400 per couple For Past Guests
    • No Tipping Required

    Fly Cruise from

    • Interior £1,279pp
    • Ocean View £1,429pp
    • Balcony £1,659pp

    Includes extra savings of up to £28pp

    more details

    • Next

    See More P&O Fly Cruises

    What our clients say

    Platinum Service Award Winners

    Average Customer Rating: 5/5

    2 Holidays booked ????

    Staff are always friendly and very helpful. Always leave with a great holiday to look forward to.

    Mrs Grant / February 2026

    Excellent service

    Excellent service from start to finish from Lisa at the parkhead forge Glasgow got us a fantastic holiday 5 ⭐ service would definitely recommend Stewart travel

    Trusted Customer / February 2026

    Excellent Service

    Excellent service as always

    Trusted Customer / February 2026

    Read All Reviews

    Speak to a Cruise Expert

    Call Us Free On

    0800 019 0063

    Or Enquire Online

    Get A Quote