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A cruise from San Diego is the perfect way to see the delights of the Mexican Riviera to the south or further up the Californian coast along the western seaboard all the way north to Vancouver, even as a one-way trip. Alternatively, there are also many itineraries departing for round-trip sailings to Hawaii. Typically with a duration of 7 to 10 days, whether you're a couple, family or solo traveller, and with plenty of flights options out of the UK to San Diego International Airport, you'll easily find the best cruise departing San Diego for you for 2027, 2028 and 2029 with Stewart Travel. Call one of our friendly Cruise Experts and book your dream San Diego cruise adventure today!
Koningsdam 21 November 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Guayamas - San Diego
Cruise Only from
Includes extra savings of up to £44pp
Disney Wonder 22 November 2026 7 nights
Itinerary: San Diego - Mazatlan - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Serenade of the Seas 22 November 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - San Diego
Call us now on 0800 917 5742
Koningsdam 28 November 2026 10 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - Puerto Vallarta - San Diego
Cruise Only from
Includes extra savings of up to £74pp
Disney Wonder 29 November 2026 5 nights
Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Zaandam 07 December 2026 12 nights
Itinerary: San Diego - Cabo San Lucas - Guayamas - Topolobampo - La Paz - Mazatlan - Puerto Vallarta - Ensenada - San Diego
Cruise Only from
Includes extra savings of up to £130pp
Koningsdam 08 December 2026 11 nights
Itinerary: San Diego - Manzanillo - Puerto Vallarta - Mazatlan - La Paz - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £107pp
Serenade of the Seas 13 December 2026 7 nights
Itinerary: San Diego - Catalina Island - Ensenada - Cabo San Lucas - San Diego
Cruise Only from
Koningsdam 19 December 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - San Diego
Cruise Only from
Includes extra savings of up to £92pp
Koningsdam 19 December 2026 14 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - San Diego - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £182pp
Zaandam 19 December 2026 15 nights
Itinerary: San Diego - Cabo San Lucas - Puerto Vallarta - Santa Cruz - Puerto Quetzal - Puntarenas - Cartagena - Fort Lauderdale
Call us now on 0800 917 5742
Serenade of the Seas 20 December 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - San Diego
Cruise Only from
Includes extra savings of up to £40pp
Norwegian Star 20 December 2026 6 nights
Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - San Diego
Cruise Only from
Luxury
Crystal Serenity 21 December 2026 9 nights
Itinerary: San Diego - Topolobampo - Loreto - La Paz - San Diego
Cruise Only from
Luxury
Crystal Serenity 21 December 2026 18 nights
Itinerary: San Diego - Topolobampo - Loreto - La Paz - San Diego - Manzanillo - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego
Cruise Only from
Disney Wonder 22 December 2026 7 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - San Diego
Cruise Only from
Norwegian Star 26 December 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego
Cruise Only from
Includes extra savings of up to £66pp
Koningsdam 26 December 2026 7 nights
Itinerary: San Diego - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £76pp
Koningsdam 26 December 2026 14 nights
Itinerary: San Diego - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego - Cabo San Lucas - La Paz - Guayamas - San Diego
Cruise Only from
Includes extra savings of up to £175pp
Serenade of the Seas 27 December 2026 7 nights
Itinerary: San Diego - Mazatlan - La Paz - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £95pp
Excellent service throughout
Trusted Customer / November 2026
Very informative and helpful. Complete understanding of our needs and delivered on recommendation and price.
Mrs Brown / November 2026
Another excellent experience, booking my next holiday, from the ladies at the Helensburgh branch. Always very welcoming when you enter their premises, and every so helpful and friendly at helping you find the right holiday for you. Add to that, when they ask how your previous trip went, and love to hear your stories. They're genuinely interested in their customers, and their needs.
Mr Cornish / November 2026
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