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Home / Cruise Lines / Oceania Cruises / Sirena / Rome to Istanbul Cruise

Rome to Istanbul Cruise

  • Departure DateThu 5th Nov 2026
  • Oceania Cruises Sirena
  • 7 Night Cruise From Rome
  • Cruise Only From £1,549 pp

Itinerary

  • Rome
  • Naples, Italy
  • Sicily
  • Malta
  • Athens
  • Mitilene (Lesbos), Grecia
  • Istanbul

What's Included

  • Gratuities
  • Unlimited WiFi
  • Gourmet Speciality Dining
  • Soft Drinks, Bottled Water, Speciality Tea & Coffee
  • In Suite & Stateroom Dining
  • Luxurious accommodation in stylish staterooms on board Mid-sized, elegant ships
  • Finest cuisine at sea, served in a variety of distinctive open-seating restaurants, all at no additional charge
  • 24-hour room service
  • WiFi
  • Overseas Shuttle Service on selected journeys
  • Concierge Level Staterooms with exclusive Privileges including access to Concierge Lounge
  • 24-hour Butler service & additional amenities in Penthouse Suites and above including: Priority embarkation & luggage delivery, in-suite dining, garment pressing & shoe shine service & welcome bottle of Champagne

Prices from pp

TypeInteriorOcean ViewBalconySuite
Cruise Only
£1,549
£1,659
£2,459
£3,399

Includes extra savings of up to £179pp
Single Cruise Only prices available from £2,889
Cruise Only - price based on cruise only, call to add flights from your regional airport.
Voyage Code: SIR261105

Speak to a Cruise Expert

Day 1 - Rome

Arrive: Thu 05 November 2026 / Depart: Thu 05 November 2026 at 17:00

Your gateway to the Eternal City, Civitavecchia has served as Rome's seaport since the 13th century. The port has a long and venerable history. The emperor Trajan built a pleasure villa near the modern city, while Bernini and Michelangelo designed the harbor fortifications. Yet the Eternal City eternally beckons. The ancient capital of the Western World and the center of Christianity for nearly 2,000 years, Rome provides an inexhaustible feast. Visit the ruins of the Forum, view the splendors of the Sistine Chapel, or climb the Spanish Steps, once the heart of Rome's Bohemian Quarter. Rome has been a magnet luring the world's greatest artists, architects, and philosophers since the days of the Caesars.

Day 2 - Naples, Italy

Arrive: Fri 06 November 2026 at 07:00 / Depart: Fri 06 November 2026 at 18:00

Spend a day exploring the fabulous ruins of ancient Pompeii or Herculaneum with their stunning temples, frescoes and mosaics. Explore fascinating Naples and its famed museums, visit charming Sorrento or take a boat trip to the beautiful Isle of Capri.

Day 3 - Sicily

Arrive: Sat 07 November 2026 at 07:00 / Depart: Sat 07 November 2026 at 19:00

Visit beautiful Taormina and marvel at its famous Greek theater and the stunning view of Mount Etna. Explore lovely medieval Messina with its historic churches and the cathedral where it is rumored Richard the Lionheart worshipped in 1190. Or discover ancient Tyndaris, founded in 396 B.C., with its fine mosaics, Roman baths and impressive theater overlooking the sea.

Day 4 - Malta

Arrive: Sun 08 November 2026 at 07:00 / Depart: Sun 08 November 2026 at 19:00

Discover the myriad of cultural layers of Malta, from its amazing prehistoric temples at Tarxien to beautiful walled medieval Mdina, nearby Rabat, and Marsaxlokk, a colorful fishing village. Admire the stunning scenery and wander through imposing churches and down the streets of fortified towns where the Knights of St. John once held sway.

Day 5 - At Sea

Day 6 - Athens

Arrive: Tue 10 November 2026 at 07:00 / Depart: Tue 10 November 2026 at 17:00

Climb up the magnificent Acropolis and stand in awe of the Parthenon, the beautiful temples and the view over Athens stretched out before you. See city highlights including the new and old Olympic stadiums. Journey to Cape Sounion and the temple of Poseidon overlooking the sea, or visit ancient Corinth and the narrow Corinth Canal cut through miles of solid rock.

Day 7 - Mitilene (Lesbos), Grecia

Arrive: Wed 11 November 2026 at 07:00 / Depart: Wed 11 November 2026 at 14:00

Explore this bustling city's ancient roots, and visit the huge castle perched on the hill - the beautiful Greek theater that the Romans repaired and then copied back in Rome! See the impressive Cathedral and the Church of St. Nicholas, converted from a mosque. Enjoy the Archaeological Museum or one of the fine art museums with collections of important works. Venture into the old quarter near the waterfront to enjoy the old Turkish mansions or into the countryside and discover quaint villages where time has stopped.

Day 8 - Istanbul

Arrive: Thu 12 November 2026 at 08:00 / Depart: Thu 12 November 2026

Indulge your eyes and senses in this magnificent city astride two continents. Visit beautiful Topkapi Palace, the awesome Hagia Sophia and the impressive Blue Mosque. Cruise the Bosphorus to see the city and its surroundings from another perspective. Visit one of the many museums or stroll through the spice market and the famous Grand Bazaar.

Sirena From Oceania Cruises

Elegant sister ship to charming Regatta, Insignia and Nautica, Oceania Cruises’ newest addition, Sirena embodies the most treasured elements of our celebrated fleet, and features a few highlights all her own. With the introduction of two culinary experiences, Sirena offers even more ways to savor The Finest Cuisine at Sea. Tuscan Steak, a new specialty restaurant, serves Italian favorites, succulent steaks and fresh seafood inspired by Toscana and Polo Grill. The Grand Dining Room offers a surprise transformation into The Bistro during lunch, which serves classic French fare as well as regional specialties and lunchtime favorites. Also featuring the beloved restaurant Red Ginger, Sirena invites you to enjoy bold Asian cuisine in a fresh new way.

Ship Cabins

Inside Stateroom

Beautifully re-designed with a modern flair, these delightful private retreats boast 160 square feet of luxury. Highlights include a comfortable seating area, vanity desk, refrigerated mini-bar and plenty of storage. The ingenious use of space is complemented by the re-inspired decor. Inside Stateroom FREE Amenities: FREE soft drinks replenished daily in your refrigerated mini-bar FREE still & sparkling Vero Water FREE room service menu 24 hours a day Inside Stateroom Included Amenities: Ultra Tranquility Bed, an Oceania Cruises Exclusive Bulgari amenities Twice-daily maid service Interactive television system with on-demand movies, weather and more Wireless Internet access and cellular service Writing desk and stationary Plush cotton towels, robes and slippers Handheld hair dryer Security safe Belgian chocolates with turndown service

Deluxe Ocean View Stateroom

With entirely re-designed closets, dressers and vanities, these 165-squarefoot staterooms feel even more spacious. A generous seating area, vanity desk, refrigerated mini-bar and breakfast table are perfectly complemented by the soothing hues and stylish fabrics of the sleek new decor. Deluxe Ocean View Stateroom FREE Amenities: FREE soft drinks replenished daily in your refrigerated mini-bar FREE still & sparkling Vero Water FREE room service menu 24 hours a day Deluxe Ocean View Stateroom Included Amenities: Ultra Tranquility Bed, an Oceania Cruises Exclusive Bulgari amenities Twice-daily maid service Category (C1) includes accessibility features in stateroom #4052 and #4056. Interactive television system with on-demand movies, weather and more Wireless Internet access and cellular service Writing desk and stationary Plush cotton towels, robes and slippers Handheld hair dryer Security safe Belgian chocolates with turndown service Deluxe Ocean View Accessibility Features: Bed with hoist space Large bathroom door Toilet grab rails Roll in bathrooms with no lip riser which has a wraparound drainage system as well as a bathtub

Ocean View Stateroom

Either featuring a classic porthole or a panorama window with obstructed views, these exquisitely appointed 165-square-foot staterooms showcase sophisticated new decor and a modern design that maximizes both space and convenience. Enjoy a comfortable seating area with a sofa on which to stretch out, as well as a vanity desk, breakfast table and refrigerated mini-bar. Ocean View FREE Amenities: FREE soft drinks replenished daily in your refrigerated mini-bar FREE still & sparkling Vero Water FREE room service menu 24 hours a day Ocean View Included Amenities: Ultra Tranquility Bed, an Oceania Cruises Exclusive Bulgari amenities Twice-daily maid service Interactive television system with on-demand movies, weather and more Wireless Internet access and cellular service Writing desk and stationary Plush cotton towels, robes and slippers Handheld hair dryer Security safe Belgian chocolates with turndown service

Solo Oceanview Stateroom

These charming 143-square-foot staterooms are the perfect retreat for the solo traveler. Amply spacious and centrally located on Deck 6, each is equipped with a sublimely plush Tranquility Bed, refrigerated mini-bar, writing desk and abundant storage space. Stateroom Amenities : Tranquility Bed, an Oceania Cruises exclusive FREE sodas replenished daily in your refrigerated mini-bar FREE still and sparkling Vero Water Private teak veranda Luxury bath amenities FREE room service menu 24 hours a day Daily housekeeping service Gourmet turndown chocolates upon request Interactive television system with on-demand movies, weather and more Starlink® WiFi service Writing desk and stationery Plush cotton towels, robes and slippers Handheld hair dryer Security safe

Concierge Veranda

Located in some of the most desirable locations on the ship, Category A Concierge Level Veranda Staterooms offer the attractive blend of both value and luxury. These sleekly redefined 216-square-foot staterooms offer coveted amenities and exclusive privileges, such as free laundry service, that make your experience that much more carefree. Fresh new decor, sumptuous Ultra Tranquility Beds and re-inspired verandas with stylish new furniture complete the Concierge experience. Exclusive Concierge Privileges In addition to Stateroom Amenities FREE laundry service – up to 3 bags per stateroom+ Expanded lunch and dinner room service menu from The Grand Dining Room Priority noon ship embarkation Complimentary welcome bottle of Champagne Priority online specialty restaurant reservations Unlimited access to the Aquamar Spa Terrace iPad upon request for your enjoyment onboard++ Complimentary Oceania Cruises logo tote bag Cashmere lap blankets, perfect for relaxing on your veranda Complimentary pressing of garmets upon embarkation++ Complimentary shoeshine service

Veranda Stateroom

Custom-crafted furnishings, exotic stone finishes, supple upholstered headboards and chic lighting are just a few of the enhancements within these 216-square-foot staterooms that also boast our most popular luxury – a private teak veranda for watching the ever-changing panoramas. Conveniences within each stateroom include a vanity desk, refrigerated mini-bar, breakfast table and spacious seating area. Veranda Stateroom Amenities Ultra Tranquility Bed, an Oceania Cruises Exclusive Refrigerated mini-bar with free and unlimited soft drinks and bottled water replenished daily Private teak veranda Complimentary 24-hour room service Signature Belgian chocolates with nightly turndown service Plush cotton towels Thick cotton robes and slippers Bulgari amenities Handheld hair dryer Flat-screen television with DVD player and extensive media library Security safe

Owner's Suite

Lavish new fabrics and designer furnishings grace our six new Owner’s Suites – always among the first to be reserved. Immensely spacious and exceptionally luxurious, these suites span nearly 1,000 square feet and are oases of quietude and relaxation. Every imaginable amenity is found here, further enhanced by a sumptuous re-designed bathroom with an oversized shower, a private teak veranda and two flat-screen televisions. Owner's Suite Privileges In addition to Stateroom Amenities FREE laundry service – up to 3 bags per stateroom+ Priority 11 am ship embarkation with priority luggage delivery 24-hour Butler service Complimentary in-suite bar setup with 6 full-size bottles of premium spirits and wines from our suite beverage menu Complimentary welcome bottle of Champagne Fresh fruit basket replenished daily Priority online specialty restaurant reservations Unlimited access to the Aquamar Spa Terrace iPad upon request for your enjoyment on board++ Customized entertainment system Bulgari gift set and variety of amenities Choice of daily printed newspaper Complimentary Oceania Cruises logo tote bag and personalized stationery Cashmere lap blankets, perfect for relaxing on your veranda Choice of pillow from a luxurious selection Complimentary shoeshine service Complimentary pressing of garments upon embarkation++

Penthouse Suite

Our collection of 322-square-foot Penthouse Suites is designed with splendid décor and exquisite furnishings in serene shades of the sea and sun. Spacious enough for private in-suite dining the living area features a refrigerated mini-bar and vanity desk, and the granite-clad bathroom features a large enclosed shower. Relax on the beautifully furnished private teak veranda. Penthouse Suite Privileges In addition to Suite & Stateroom Amenities Free laundry service – up to 3 bags per stateroom+ Priority 11 am ship embarkation with priority luggage delivery 24-hour Butler service Complimentary welcome bottle of Champagne Priority online specialty restaurant and shore excursion reservation Unlimited access to the Aquamar Spa Terrace iPad upon request Variety of Bulgari amenities Complimentary Oceania Cruises logo tote bag Cashmere lap blankets Complimentary shoe shine service Complimentary pressing of garments upon embarkation++ +Up to 20 garments per laundry bag. 3 day turnaround time and laundry will not be accepted 3 days prior to disembarkation.

Vista Suite

Named for their sweeping views over the ship's bow, the four Vista Suites each sprawl over 786 square feet. Every imaginable comfort is here, including a second bathroom for guests as well as a master bathroom newly redesigned in onyx and granite with a luxurious new shower. Relax on the private teak veranda, listen to music in enhanced surround sound or watch a movie on one of two flat-screen televisions. Access wireless Internet on a complimentary iPad. Vista Suite Privileges In addition to Stateroom Amenities FREE laundry service – up to 3 bags per stateroom+ Priority 11 am ship embarkation with priority luggage delivery 24-hour Butler service Complimentary in-suite bar setup with 6 full-size bottles of premium spirits and wines from our suite beverage menu Complimentary welcome bottle of Champagne Fresh fruit basket replenished daily Priority online specialty restaurant reservations Unlimited access to the Aquamar Spa Terrace iPad upon request for your enjoyment on board++ Bulgari gift set and variety of amenities Choice of daily printed newspaper Complimentary Oceania Cruises logo tote bag and personalized stationery Cashmere lap blankets, perfect for relaxing on your veranda Choice of pillow from a luxurious selection Complimentary shoeshine service Complimentary pressing of garments upon embarkation++
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