20 nights South Caribbean from Genoa (Portofino) Cruise

Day 1 - Genoa

Arrive: Fri 30 October 2026 / Depart: Fri 30 October 2026 at 18:00

Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size.

Day 2 - Florence/Pisa

Arrive: Sat 31 October 2026 at 08:00 / Depart: Sat 31 October 2026 at 18:00

On the west coast of Tuscany lies the cosmopolitan port city of Livorno, an MSC Mediterranean Cruises destination. This Italian getaway is known for its historical architecture, sumptuous seafood, and checkboard waterside promenade. Livorno is the perfect launch pad for visiting Tuscany’s beautiful art cities, Florence and Pisa. What’s more, you’ll find great natural environments, like Macchia della Magona, spread across the region.

Day 3 - Marseille, France

Arrive: Sun 01 November 2026 at 09:00 / Depart: Sun 01 November 2026 at 18:00

On the spectacular coastline of the French Riviera lies Marseille, an MSC Mediterranean Cruises destination. This atmospheric port city is known for its unique mix of grit and glamour, seen in its labyrinth of streets and historical architecture. Only a few miles from Marseille’s charismatic cafes and bustling Vieux Port, stunning cities are to be found. Visit Aix-en-Provence, birthplace of Cézanne, or take in the ancient beauty of Avignon.

Day 4 - Barcelona

Arrive: Mon 02 November 2026 at 07:00 / Depart: Mon 02 November 2026 at 16:00

One of the busiest cruise ports in the Mediterranean, the seaside city of Barcelona is known for its iconic architecture, colourful culture, and world-class drinking and dining. Explore Antoni Gaudí’s surreal Sagrada Família, the famous boulevard of the Ramblas, the medieval Barri Gótic, and the Museu Picasso. But there’s even more to discover in this sprawling Spanish city, an MSC Mediterranean Cruises destination: from hidden tapas bars and fabulous food markets to Europe’s biggest football stadium.

Day 5 - At Sea

Day 6 - Tangier, Morocco

Arrive: Wed 04 November 2026 at 08:00 / Depart: Wed 04 November 2026 at 17:00

Settled on the Strait of Gibraltar, Tangier, an MSC Mediterranean Cruises destination, is an energetic and multicultural port. This magical Moroccan city is distinguished by its whitewashed Medina, maze of evocative alleys, bustling squares, and fascinating people. Glimpse the Dar el Makhzen palace, the Church of Saint Andrew, Jardins de la Mendoubia park, and the famous Bab Al Fahs gate. Further afield, visit natural wonders including the surreal Caves of Hercules.

Day 7 - At Sea

Day 8 - At Sea

Day 9 - At Sea

Day 10 - At Sea

Day 11 - At Sea

Day 12 - At Sea

Day 13 - At Sea

Day 14 - St. John's, Newfoundland, Canada

Arrive: Thu 12 November 2026 at 09:00 / Depart: Thu 12 November 2026 at 18:00

A One-of-a-Kind Natural Microcosm Wild landscapes, valleys dotted with farms, fishing villages, parks and islands all along the coast: all of this and more awaits you in New Brunswick, a beautiful maritime province in French Canada. Your MSC cruise will take you on the discovery of a natural land filled with a thousand secrets, surprising you with its magnificent coastline, mountains, forests and rivers, as well as the variety of wild animals that live there including bears, whales, moose and seals. This region is home to one of the oldest cities in Canada overlooking the beautiful Bay of Fundy: Saint John. There is no other place in the Maritimes with the same urban charm of a historic city balanced with the grandiose, natural charm of a bay famous for its impressive tides. On your MSC cruise, you will have a chance to discover this port city with its delightful Victorian architecture and steep historical streets, watch the ships dock at the port and admire the restaurants and shops near historic sites such as the New Brunswick Museum, home to the Hall of Great Whales and three floors of fascinating galleries . Saint John City Market is also not to be missed as it is the oldest agricultural market in North America: its beams are reminiscent of a ship's inverted hull offering a unique shopping experience. In Saint John, there is a natural microcosm that awaits you, especially in the Bay of Fundy where you can observe a truly unique phenomenon: the highest and most powerful tides in the world that can reach up to 16 m high. The surrounding landscape has been sculpted by billions of tons of water pouring in and out of the bay twice daily. The Bay of Fundy is also home to Hopewell Rocks Park, a group of rock formations that dot the water like islands during high tide and seem to be towers during low tide.

Day 15 - Philipsburg, Sint Maarten

Arrive: Fri 13 November 2026 at 09:00 / Depart: Fri 13 November 2026 at 18:00

Offering some of the best vistas in all the Caribbean, St. Maarten is the smallest inhabited island in the world shared by two nations - France in the north and the Netherlands in the south. Dubbed the true melting pot of the Caribbean, the 37-square-mile island is home to people of 47 different nationalities and more than 400 restaurants, featuring a hugely diverse variety of cuisine. The island also has two capitals: Philipsburg on the Dutch side, and Marigot in the French part. Once you arrive on an MSC Caribbean and Antilles cruise in St. Maarten, explore how the two cultures have blended their very distinct characters on one of our MSC excursions. Your St. Maarten cruise will dock in Philipsburg, founded in 1763 by John Philips, a Scottish captain in the Dutch Navy. Philipsburg, with its pastel-coloured West Indian houses, is known for its duty-free shopping along Front Street, the Great Salt Pond, which once made the island literally “worth its salt,” and attracted the attention of the French, and Fort Willem, built in 1801, with mag-nificent views of the bay and the surrounding islands. From there, several MSC excursions take you on a hilly drive to the French side of the island to experience Marigot. Originally a fishing village on a swamp for which it was named, Marigot became the capital during the reign of Louis XVI. Fort Louis, which overlooks Marigot Bay and Anguilla, was built in the late 18th century to protect the town’s warehouses of salt, coffee, sugar cane and especially rum from the English. Today, Marigot showcases quaint colourful gingerbread-like houses, tasty sidewalk bistros and a waterfront market selling fruit and vegetables, spices, local meats and fresh fish from Creole huts worth exploring. For something special, spend the day on the Dutch side of the island at the restored sugar planta-tion at Rockland Estate. Take in a history lesson at the Emilio Wilson Museum or a nature hike and 360-degree views from Sentry Hill. Participate in a hands-on cooking demonstration of authentic local cuisines with lunch at Emilio’s restaurant, in an exclusive Martha Stewart excursion curated for MSC Cruises. Also at Rockland Estate, thrill seekers can book other MSC excursions on the Flying Dutchman, a fast and furious zip line ride that will have you whizzing down the line at speeds of up to 56 mph (90 km) per hour. Then take the Pirate Sky Ride cable car back up the top to the Crow’s Nest where several platforms encircling the mountain afford panoramic views of the neighbouring islands of Saba, Sint Eustatius, Saint Barthélemy and Anguilla. Then plunge down the mountain on a Schooner Ride inner tube along a specially designed track. To experience one of the island’s hottest spots and most popular attractions, visit the famous Maho Beach, also called Airplane Beach. Don’t get too comfortable, though. This is because you watch as planes pass only a short distance above your head as they land and take off from Princess Juli-ana Airport’s short runway next door.

Day 16 - St. Kitts

Arrive: Sat 14 November 2026 at 08:00 / Depart: Sat 14 November 2026 at 18:00

An MSC Caribbean and Antilles cruise to St. Kitts and Nevis will introduce you to the sister volcanic islands of the Caribbean. These islands have been a premier destination for elite tourists for more than 200 years and served as a haven for European nobility in the 19th and 20th centuries. Basseterre, founded by the French in 1625, became the capital of St. Kitts in 1727, when the Eng-lish took over the island. It remained under British rule until the islands declared their independence in 1983. Throughout the city’s long history, natural disasters and conflicts have afflicted Basseterre; most buildings date from the latter part of the 1800s. A visit to the city’s two cathedrals, St. George’s Anglican Church and the Catholic Cathedral of Immaculate Conception, will appeal to those with a love of history and architecture. On South Square Street, visit Georgian House, one of the better-preserved examples of local 18th-century architecture. Leaving Basseterre, take a panoramic drive on an MSC excursion to the southeast peninsula en route for a kayaking adventure. Stop at Timothy Hill to enjoy a 360-degree view and a stunning glimpse of the Atlantic and Caribbean nearly side by side; the two bodies of water, each with a dis-tinct appearance, are separated by a spit of land. If it is adrenaline that quenches your thirst, go off-road on an excursion into the interior of St. Kitts in a specially modified 4x4 Land Rover to explore the lush rainforest and spot shy, green monkeys and other exotic tropical flora and fauna. At a private mountaintop property, 1,000 feet above sea level, enjoy amazing vistas of the rainforest, the coastline, Basseterre, and the neighbouring island of Nevis. Continue your journey through the mountains to the opposite side of the island to explore quaint villages and experience country life. Learn about wearable art at Romney Manor, home of the world-famous Caribelle Batik. Visit the demonstration room, where acclaimed artists present the wax and dye process of batik making. The Romney Manor Estate encompasses eight acres of historical ruins and features ancient Carib Indian rock drawings and a beautiful botanical garden. For an excursion unlike any other, book a land-and-sea tour combining train and catamaran. In the first leg of the trip, take in the scenery of St. Kitts on a narrow-gauge train, followed by a catama-ran cruise. The St. Kitts Scenic Railway has been showing visitors the island since 2003, but be-fore that it had transported sugar cane from the fields to the sugar mill in Basseterre for nearly 100 years. At the end of the train journey, board a catamaran to sail the storied western coast of the is-land and take in its gorgeous views. Fly through the rainforest 25 stories above the ground as you enjoy a spectacular zipline tour over a network of 5 cable lines at the historic Wingfield Estate. Enjoy fantastic panoramic views of Brimstone Hill National Fortress (a UNESCO World Heritage Site), Old Road Village, former sugar estates, the Caribbean Sea and Mount Liamuiga, with its volcano crater ridge marking the highest point in St. Kitts.

Day 17 - At Sea

Day 18 - La Romana

Arrive: Mon 16 November 2026 at 07:00 / Depart: Mon 16 November 2026 at 23:30

La Romana is a city on the Dominican Republic’s Caribbean coast and a gateway to nearby resort areas. Overlooking the Chavón River, Altos de Chavón is a re-created 16th-century Mediterranean village with artists' workshops. An obelisk painted with colorful images of local life stands in the city center. South of the city is Catalina Island, with beaches, coral reefs and the wrecked ship of pirate William Kidd.

Day 19 - Catalina Island, Dominican Republic

Arrive: Tue 17 November 2026 at 07:00 / Depart: Tue 17 November 2026 at 17:00

Day 20 - At Sea

Day 21 - Barbados

Arrive: Thu 19 November 2026 at 09:00 / Depart: Thu 19 November 2026

When you arrive in Barbados on an MSC Caribbean and Antilles cruise, begin your exploration with the capital, Bridgetown. There are many attractions in this small Caribbean city, but by all means pause to admire its many colonial buildings, the Parliament Building and the statue of Lord Nelson standing in what is currently called the National Heroes Square. Barbados has retained somewhat of a British feel, with its place names, cricket, horse-racing and polo, Anglican parish churches and even a hilly district known as Scotland. But the Britishness can be exaggerated, for this is a distinctly West Indian country, covered by a patch-work of sugarcane fields and dotted with tiny rum shops. The Garrison Historic Area, a UNESCO World Heritage Site with magnificent 18th- and 19th-century buildings, is a must-see stop, featuring one of the world's finest collection of cannons. It also includes the George Washington House, where the American patriot spent six weeks of his life. The current St. John's Church, in the eastern parish of the same name, is the fifth reconstruction of the oldest local church, in Barbadian Gothic style. Perched on a cliff 800 feet above the sea, it dates back to 1836. Its interior hosts a sculpture by 18th-century British artist Richard Westmacott, while its churchyard contains the tomb of Ferdinando Paleologus, a direct descendant of the brother of Constantine XI, the last Byzantine emperor. Book an MSC excursion to discover the island’s history at the Barbados Museum and Historical Society in the St. Michael neighbourhood. And tour Sunbury Plantation House, located in the tranquil St. Philip countryside. Dating back to 1650, it’s a living monument to plantation life and a bygone era. Harrison’s Cave, in St. Thomas district, is a wonder of nature with its stalactites, stalagmites, streams, lakes and waterfalls. In one of the caverns, the play of light on the rocks is so in-tense that it has been nicknamed “The Crystal Room”. For some fun at the beach, head to Pirates Cove, one of the best beaches on Barbados. Featuring palm trees and chickee huts, white sand and crystal-clear water, it’s the perfect place to relax, just a stone’s throw from Bridgetown. If you’re brave enough to dive into the deep, set out on an MSC excursion inside a real submarine, the Atlantis, to explore the coral reef and discover the beauty that the depths reveal.