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P&O Fly Cruises to the Mediterranean

Find the best P&O fly cruise to the Mediterranean for you in 2026, 2027 and 2028 with Stewart Travel below. Call one of our Cruise Experts on 0800 019 0063 to book your dream fly cruise holiday today!

P&O Fly Mediterranean Cruises

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    Western Mediterranean

    P&O Cruises

    Azura 21 May 2026 7 nights

    Itinerary: Malta - Rome - Florence/Pisa - Cannes - Ajaccio - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £739pp
    • Ocean View £769pp
    • Balcony £989pp

    Includes extra savings of up to £10pp

    more details

    Mediterranean

    P&O Cruises

    Azura 21 May 2026 14 nights

    Itinerary: Malta - Rome - Florence/Pisa - Cannes - Ajaccio - Malta - Mykonos - Athens - Chania - Katakolon...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,579pp
    • Ocean View £1,579pp
    • Balcony £1,779pp

    Includes extra savings of up to £56pp

    more details

    Greek Islands

    P&O Cruises

    Azura 28 May 2026 7 nights

    Itinerary: Malta - Mykonos - Athens - Chania - Katakolon - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £769pp
    • Ocean View £789pp
    • Balcony £1,229pp

    Includes extra savings of up to £12pp

    more details

    Mediterranean

    P&O Cruises

    Azura 28 May 2026 14 nights

    Itinerary: Malta - Mykonos - Athens - Chania - Katakolon - Malta - Catania - Dubrovnik - Corfu - Taranto...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,479pp
    • Ocean View £1,529pp
    • Balcony £2,469pp

    Includes extra savings of up to £25pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 04 June 2026 7 nights

    Itinerary: Malta - Catania - Dubrovnik - Corfu - Taranto - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,029pp
    • Ocean View £1,139pp
    • Balcony £1,329pp

    Includes extra savings of up to £21pp

    more details

    Mediterranean

    P&O Cruises

    Azura 04 June 2026 14 nights

    Itinerary: Malta - Catania - Dubrovnik - Corfu - Taranto - Malta - Santorini - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,629pp
    • Ocean View £1,959pp
    • Balcony Call Us

    Includes extra savings of up to £20pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 11 June 2026 7 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,059pp
    • Ocean View £1,109pp
    • Balcony £1,179pp

    Includes extra savings of up to £12pp

    more details

    Mediterranean

    P&O Cruises

    Azura 11 June 2026 14 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta - Taranto - Corfu - Kefalonia - Catania...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,429pp
    • Ocean View £1,629pp
    • Balcony £2,989pp

    Includes extra savings of up to £38pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 18 June 2026 7 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,029pp
    • Ocean View £1,079pp
    • Balcony £1,179pp

    Includes extra savings of up to £20pp

    more details

    Mediterranean

    P&O Cruises

    Azura 18 June 2026 14 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta - Calvi - Florence/Pisa - Rome - Naples...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,379pp
    • Ocean View £1,529pp
    • Balcony £1,879pp

    Includes extra savings of up to £42pp

    more details

    Western Mediterranean

    P&O Cruises

    Azura 25 June 2026 7 nights

    Itinerary: Malta - Calvi - Florence/Pisa - Rome - Naples - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £889pp
    • Ocean View £939pp
    • Balcony £1,079pp

    Includes extra savings of up to £20pp

    more details

    Mediterranean

    P&O Cruises

    Azura 25 June 2026 14 nights

    Itinerary: Malta - Calvi - Florence/Pisa - Rome - Naples - Malta - Mykonos - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,379pp
    • Ocean View £1,529pp
    • Balcony £2,049pp

    Includes extra savings of up to £37pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 02 July 2026 7 nights

    Itinerary: Malta - Mykonos - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £939pp
    • Ocean View £1,179pp
    • Balcony £1,279pp

    Includes extra savings of up to £21pp

    more details

    Mediterranean

    P&O Cruises

    Azura 02 July 2026 14 nights

    Itinerary: Malta - Mykonos - Rhodes - Ephesus - Athens - Malta - Taranto - Corfu - Kefalonia - Catania...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,509pp
    • Ocean View £1,679pp
    • Balcony £2,169pp

    Includes extra savings of up to £39pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 09 July 2026 7 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Top Deal
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £989pp
    • Ocean View £1,009pp
    • Balcony £1,079pp

    Includes extra savings of up to £11pp

    more details

    Mediterranean

    P&O Cruises

    Azura 09 July 2026 14 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta - Chania - Athens - Mykonos - Heraklion...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,579pp
    • Ocean View £1,679pp
    • Balcony £2,069pp

    Includes extra savings of up to £40pp

    more details

    Greek Islands

    P&O Cruises

    Azura 16 July 2026 7 nights

    Itinerary: Malta - Chania - Athens - Mykonos - Heraklion - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £839pp
    • Ocean View £939pp
    • Balcony £1,059pp

    Includes extra savings of up to £20pp

    more details

    Mediterranean

    P&O Cruises

    Azura 16 July 2026 14 nights

    Itinerary: Malta - Chania - Athens - Mykonos - Heraklion - Malta - Corfu - Kotor - Split - Dubrovnik...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,609pp
    • Ocean View £1,729pp
    • Balcony £2,619pp

    Includes extra savings of up to £46pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 23 July 2026 7 nights

    Itinerary: Malta - Corfu - Kotor - Split - Dubrovnik - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,329pp
    • Ocean View £1,379pp
    • Balcony £1,559pp

    Includes extra savings of up to £16pp

    more details

    Mediterranean

    P&O Cruises

    Azura 23 July 2026 14 nights

    Itinerary: Malta - Corfu - Kotor - Split - Dubrovnik - Malta - Mykonos - Athens - Chania - Katakolon...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,829pp
    • Ocean View £1,859pp
    • Balcony £2,319pp

    Includes extra savings of up to £38pp

    more details

    Greek Islands

    P&O Cruises

    Azura 30 July 2026 7 nights

    Itinerary: Malta - Mykonos - Athens - Chania - Katakolon - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £919pp
    • Ocean View £969pp
    • Balcony £1,129pp

    Includes extra savings of up to £11pp

    more details

    Mediterranean

    P&O Cruises

    Azura 30 July 2026 14 nights

    Itinerary: Malta - Mykonos - Athens - Chania - Katakolon - Malta - Rome - Florence/Pisa - Cannes - Ajaccio...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,579pp
    • Ocean View £1,729pp
    • Balcony £1,999pp

    Includes extra savings of up to £20pp

    more details

    Western Mediterranean

    P&O Cruises

    Azura 06 August 2026 7 nights

    Itinerary: Malta - Rome - Florence/Pisa - Cannes - Ajaccio - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £989pp
    • Ocean View £1,029pp
    • Balcony £1,129pp

    Includes extra savings of up to £11pp

    more details

    Mediterranean

    P&O Cruises

    Azura 06 August 2026 14 nights

    Itinerary: Malta - Rome - Florence/Pisa - Cannes - Ajaccio - Malta - Santorini - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,779pp
    • Ocean View £1,929pp
    • Balcony £2,369pp

    Includes extra savings of up to £34pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 13 August 2026 7 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,059pp
    • Ocean View £1,079pp
    • Balcony £1,129pp

    Includes extra savings of up to £25pp

    more details

    • Next

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