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P&O Fly Cruises to the Mediterranean

Find the best P&O fly cruise to the Mediterranean for you in 2026, 2027 and 2028 with Stewart Travel below. Call one of our Cruise Experts on 0800 019 0063 to book your dream fly cruise holiday today!

P&O Fly Mediterranean Cruises

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    Central Mediterranean

    P&O Cruises

    Azura 09 April 2026 7 nights

    Itinerary: Malta - Split - Zadar - Dubrovnik - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £819pp
    • Ocean View £989pp
    • Balcony £1,059pp

    Includes extra savings of up to £11pp

    more details

    Mediterranean

    P&O Cruises

    Azura 09 April 2026 14 nights

    Itinerary: Malta - Split - Zadar - Dubrovnik - Malta - Athens - Chania - Katakolon - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,579pp
    • Ocean View £1,719pp
    • Balcony Call Us

    Includes extra savings of up to £17pp

    more details

    Greek Islands

    P&O Cruises

    Azura 16 April 2026 7 nights

    Itinerary: Malta - Athens - Chania - Katakolon - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £789pp
    • Ocean View £839pp
    • Balcony £989pp

    Includes extra savings of up to £10pp

    more details

    Mediterranean

    P&O Cruises

    Azura 16 April 2026 14 nights

    Itinerary: Malta - Athens - Chania - Katakolon - Malta - Toulon - Florence/Pisa - Rome - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,179pp
    • Ocean View £1,429pp
    • Balcony £1,529pp

    Includes extra savings of up to £15pp

    more details

    Western Mediterranean

    P&O Cruises

    Azura 23 April 2026 7 nights

    Itinerary: Malta - Toulon - Florence/Pisa - Rome - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £719pp
    • Ocean View £729pp
    • Balcony £869pp

    Includes extra savings of up to £15pp

    more details

    Mediterranean

    P&O Cruises

    Azura 23 April 2026 14 nights

    Itinerary: Malta - Toulon - Florence/Pisa - Rome - Malta - Corfu - Dubrovnik - Zadar - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,379pp
    • Ocean View £1,729pp
    • Balcony £2,139pp

    Includes extra savings of up to £34pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 30 April 2026 7 nights

    Itinerary: Malta - Corfu - Dubrovnik - Zadar - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £889pp
    • Ocean View £969pp
    • Balcony £1,389pp

    Includes extra savings of up to £14pp

    more details

    Mediterranean

    P&O Cruises

    Azura 30 April 2026 14 nights

    Itinerary: Malta - Corfu - Dubrovnik - Zadar - Catania - Malta - Santorini - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,509pp
    • Ocean View £1,829pp
    • Balcony £2,319pp

    Includes extra savings of up to £34pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 07 May 2026 7 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £919pp
    • Ocean View £989pp
    • Balcony £1,429pp

    Includes extra savings of up to £14pp

    more details

    Mediterranean

    P&O Cruises

    Azura 07 May 2026 14 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta - Korcula - Zadar - Venice (Trieste) - Split...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £2,209pp
    • Ocean View £2,169pp
    • Balcony £2,949pp

    Includes extra savings of up to £60pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 14 May 2026 7 nights

    Itinerary: Malta - Korcula - Zadar - Venice (Trieste) - Split - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,179pp
    • Ocean View £1,259pp
    • Balcony £1,509pp

    Includes extra savings of up to £15pp

    more details

    Mediterranean

    P&O Cruises

    Azura 14 May 2026 14 nights

    Itinerary: Malta - Korcula - Zadar - Venice (Trieste) - Split - Malta - Rome - Florence/Pisa - Cannes - Ajaccio...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,779pp
    • Ocean View £1,779pp
    • Balcony £2,669pp

    Includes extra savings of up to £27pp

    more details

    Western Mediterranean

    P&O Cruises

    Azura 21 May 2026 7 nights

    Itinerary: Malta - Rome - Florence/Pisa - Cannes - Ajaccio - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £919pp
    • Ocean View £939pp
    • Balcony £1,129pp

    Includes extra savings of up to £21pp

    more details

    Mediterranean

    P&O Cruises

    Azura 21 May 2026 14 nights

    Itinerary: Malta - Rome - Florence/Pisa - Cannes - Ajaccio - Malta - Mykonos - Athens - Chania - Katakolon...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £2,069pp
    • Ocean View £1,679pp
    • Balcony £1,929pp

    Includes extra savings of up to £43pp

    more details

    Greek Islands

    P&O Cruises

    Azura 28 May 2026 7 nights

    Itinerary: Malta - Mykonos - Athens - Chania - Katakolon - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £919pp
    • Ocean View £1,109pp
    • Balcony £1,229pp

    Includes extra savings of up to £20pp

    more details

    Mediterranean

    P&O Cruises

    Azura 28 May 2026 14 nights

    Itinerary: Malta - Mykonos - Athens - Chania - Katakolon - Malta - Catania - Dubrovnik - Corfu - Taranto...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,779pp
    • Ocean View £1,959pp
    • Balcony £2,469pp

    Includes extra savings of up to £36pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 04 June 2026 7 nights

    Itinerary: Malta - Catania - Dubrovnik - Corfu - Taranto - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,299pp
    • Ocean View £1,379pp
    • Balcony £1,729pp

    Includes extra savings of up to £22pp

    more details

    Mediterranean

    P&O Cruises

    Azura 04 June 2026 14 nights

    Itinerary: Malta - Catania - Dubrovnik - Corfu - Taranto - Malta - Santorini - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £2,019pp
    • Ocean View £2,239pp
    • Balcony £2,619pp

    Includes extra savings of up to £26pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 11 June 2026 7 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,119pp
    • Ocean View £1,319pp
    • Balcony £1,459pp

    Includes extra savings of up to £15pp

    more details

    Mediterranean

    P&O Cruises

    Azura 11 June 2026 14 nights

    Itinerary: Malta - Santorini - Rhodes - Ephesus - Athens - Malta - Taranto - Corfu - Kefalonia - Catania...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,679pp
    • Ocean View £1,829pp
    • Balcony £2,899pp

    Includes extra savings of up to £38pp

    more details

    Central Mediterranean

    P&O Cruises

    Azura 18 June 2026 7 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £1,169pp
    • Ocean View £1,209pp
    • Balcony £1,419pp

    Includes extra savings of up to £18pp

    more details

    Mediterranean

    P&O Cruises

    Azura 18 June 2026 14 nights

    Itinerary: Malta - Taranto - Corfu - Kefalonia - Catania - Malta - Calvi - Florence/Pisa - Rome - Naples...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,559pp
    • Ocean View £1,659pp
    • Balcony £2,069pp

    Includes extra savings of up to £37pp

    more details

    Western Mediterranean

    P&O Cruises

    Azura 25 June 2026 7 nights

    Itinerary: Malta - Calvi - Florence/Pisa - Rome - Naples - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Fly Cruise from

    • Interior £989pp
    • Ocean View £1,029pp
    • Balcony £1,259pp

    Includes extra savings of up to £17pp

    more details

    Mediterranean

    P&O Cruises

    Azura 25 June 2026 14 nights

    Itinerary: Malta - Calvi - Florence/Pisa - Rome - Naples - Malta - Mykonos - Rhodes - Ephesus - Athens...

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,579pp
    • Ocean View £1,609pp
    • Balcony £2,299pp

    Includes extra savings of up to £31pp

    more details

    Eastern Mediterranean

    P&O Cruises

    Azura 02 July 2026 7 nights

    Itinerary: Malta - Mykonos - Rhodes - Ephesus - Athens - Malta

    • Direct Flights Available from London Gatwick, Belfast, Birmingham, Bristol, East Midlands, Glasgow, Manchester & Newcastle - subject to date & availability
    • New P&O All Inclusive Upgrade Package - Drinks, WiFi & Dining Credit from only £49pp per day
    • Book today from £104pp Deposit
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Fly Cruise from

    • Interior £1,029pp
    • Ocean View £1,179pp
    • Balcony £1,609pp

    Includes extra savings of up to £20pp

    more details

    • Next

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    What our clients say

    Platinum Service Award Winners

    Average Customer Rating: 4.9/5

    Fantastic service

    Diane was very pleasant and understood our requirements. Discussed choices and advice on area. Would recommend and will use again thanks

    Trusted Customer / March 2026

    Hayley was friendly and professional. She made lots of recommendations and made the changes we needed. Wouldn't hesitate to recommend to others

    Trusted Customer / March 2026

    Quick booking service

    Very quick and easy to book

    Mrs Cumlin / March 2026

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