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Holland America Cruises from San Diego, California

See all our amazing itineraries with Holland America Line sailing from San Diego below for 2026, 2027 and 2028, and find the best cruise holiday for you. Typically sailing to Hawaii, and with incredible prices and add-ons available, call one of our friendly Cruise Experts on 0800 019 0063 to book your dream Holland America cruise departing from San Diego today!

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    Wine Country & Pacific Northwest

    Holland America Line

    Nieuw Amsterdam 04 April 2026 7 nights

    Itinerary: San Diego - Catalina Island - San Francisco - Astoria - Victoria - Vancouver

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Pacific Coastal & Circle Hawaii Collector

    Holland America Line

    Nieuw Amsterdam 04 April 2026 25 nights

    Itinerary: San Diego - Catalina Island - San Francisco - Astoria - Victoria - Vancouver - Kona - Kahului - Honolulu - Nawiliwili...

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera & Sea of Cortez

    Holland America Line

    Zaandam 07 April 2026 11 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - Mazatlan - Puerto Vallarta - Manzanillo - San Diego

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,149pp
    • Ocean View £2,259pp
    • Balcony Call Us

    Includes extra savings of up to £246pp

    more details

    Baja Peninsula

    Holland America Line

    Zaandam 18 April 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera & Baja Peninsula

    Holland America Line

    Zaandam 18 April 2026 14 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Baja Peninsula, Mexican Riviera & Pacific Coast

    Holland America Line

    Zaandam 18 April 2026 18 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Catalina Island...

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 25 April 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,599pp
    • Ocean View £1,679pp
    • Balcony Call Us

    Includes extra savings of up to £108pp

    more details

    Mexican Riviera & Pacific Coast

    Holland America Line

    Zaandam 25 April 2026 11 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Catalina Island - Vancouver

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,069pp
    • Ocean View £2,179pp
    • Balcony Call Us

    Includes extra savings of up to £141pp

    more details

    Pacific Coastal

    Holland America Line

    Koningsdam 27 April 2026 5 nights

    Itinerary: San Diego - San Francisco - Vancouver

    Cruise Only from

    • Interior £429pp
    • Ocean View £509pp
    • Balcony £589pp

    more details

    Grand World Voyage

    Holland America Line

    Volendam 03 May 2026 14 nights

    Itinerary: San Diego - Manzanillo - Puerto Chiapas - Acajutla - Panama City - Cartagena - Fort Lauderdale

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,839pp
    • Ocean View £2,489pp
    • Balcony Call Us

    Includes extra savings of up to £214pp

    more details

    Panama Canal

    Holland America Line

    Nieuw Amsterdam 02 October 2026 16 nights

    Itinerary: San Diego - Puerto Vallarta - Santa Cruz - Puerto Chiapas - Puerto Quetzal - Acajutla - Cartagena - Half Moon Cay - Fort Lauderdale

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,549pp
    • Ocean View £3,649pp
    • Balcony £3,649pp

    Includes extra savings of up to £224pp

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 08 October 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £959pp
    • Ocean View £959pp
    • Balcony Call Us

    Includes extra savings of up to £77pp

    more details

    Panama Canal

    Holland America Line

    Eurodam 08 October 2026 16 nights

    Itinerary: San Diego - Cabo San Lucas - Acapulco - Santa Cruz - Puerto Chiapas - Puerto Quetzal - Puntarenas - Oranjestad - Fort Lauderdale

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,499pp
    • Ocean View £3,559pp
    • Balcony £3,559pp

    Includes extra savings of up to £224pp

    more details

    Legendary Hawaii, Tahiti & Marquesas

    Holland America Line

    Zaandam 15 October 2026 35 nights

    Itinerary: San Diego - Nawiliwili - Honolulu - Kona - Kahului - Fanning Island - Rangiroa - Huahine - Bora Bora - Raiatea...

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £5,479pp
    • Ocean View £5,479pp
    • Balcony Call Us

    Includes extra savings of up to £440pp

    more details

    Mexican Riviera & Sea of Cortez

    Holland America Line

    Koningsdam 20 October 2026 11 nights

    Itinerary: San Diego - Manzanillo - Puerto Vallarta - Mazatlan - La Paz - Loreto - Cabo San Lucas - San Diego

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,509pp
    • Ocean View £2,049pp
    • Balcony £2,049pp

    Includes extra savings of up to £111pp

    more details

    Baja Peninsula

    Holland America Line

    Koningsdam 07 November 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Classic California Coast

    Holland America Line

    Koningsdam 14 November 2026 7 nights

    Itinerary: San Diego - Catalina Island - San Francisco - Ensenada - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,039pp
    • Ocean View £1,389pp
    • Balcony £1,389pp

    Includes extra savings of up to £74pp

    more details

    Circle Hawaii Holiday

    Holland America Line

    Zaandam 19 November 2026 18 nights

    Itinerary: San Diego - Nawiliwili - Honolulu - Hilo - Kona - Kahului - Ensenada - San Diego

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,709pp
    • Ocean View £2,709pp
    • Balcony Call Us

    Includes extra savings of up to £197pp

    more details

    Circle Hawaii & Sea Of Cortez

    Holland America Line

    Zaandam 19 November 2026 30 nights

    Itinerary: San Diego - Nawiliwili - Honolulu - Hilo - Kona - Kahului - Ensenada - San Diego - Cabo San Lucas - Loreto...

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £4,409pp
    • Ocean View £4,409pp
    • Balcony Call Us

    Includes extra savings of up to £320pp

    more details

    Baja Peninsula

    Holland America Line

    Koningsdam 21 November 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,079pp
    • Ocean View £1,389pp
    • Balcony £1,389pp

    Includes extra savings of up to £77pp

    more details

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