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Holland America Cruises from San Diego, California

See all our amazing itineraries with Holland America Line sailing from San Diego below for 2026, 2027 and 2028, and find the best cruise holiday for you. Typically sailing to Hawaii, and with incredible prices and add-ons available, call one of our friendly Cruise Experts on 0800 019 0063 to book your dream Holland America cruise departing from San Diego today!

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    Mexican Riviera & Baja

    Holland America Line

    Nieuw Amsterdam 21 March 2026 14 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera

    Holland America Line

    Nieuw Amsterdam 21 March 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Baja Peninsula

    Holland America Line

    Nieuw Amsterdam 28 March 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior Call Us
    • Ocean View £1,829pp
    • Balcony £1,979pp

    Includes extra savings of up to £121pp

    more details

    Baja Peninsula, Wine Country And PNW

    Holland America Line

    Nieuw Amsterdam 28 March 2026 14 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego - Catalina Island - San Diego - San Francisco - Astoria - Victoria...

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Wine Country & Pacific Northwest

    Holland America Line

    Nieuw Amsterdam 04 April 2026 7 nights

    Itinerary: San Diego - Catalina Island - San Francisco - Astoria - Victoria - Vancouver

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,599pp
    • Ocean View £1,679pp
    • Balcony £1,939pp

    Includes extra savings of up to £118pp

    more details

    Pacific Coastal & Circle Hawaii Collector

    Holland America Line

    Nieuw Amsterdam 04 April 2026 25 nights

    Itinerary: San Diego - Catalina Island - San Francisco - Astoria - Victoria - Vancouver - Kona - Kahului - Honolulu - Nawiliwili...

    • FREE $400 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera & Sea of Cortez

    Holland America Line

    Zaandam 07 April 2026 11 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - Mazatlan - Puerto Vallarta - Manzanillo - San Diego

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,149pp
    • Ocean View £2,259pp
    • Balcony Call Us

    Includes extra savings of up to £94pp

    more details

    Baja Peninsula

    Holland America Line

    Zaandam 18 April 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,599pp
    • Ocean View £1,679pp
    • Balcony Call Us

    Includes extra savings of up to £269pp

    more details

    Mexican Riviera & Baja Peninsula

    Holland America Line

    Zaandam 18 April 2026 14 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,579pp
    • Ocean View £2,709pp
    • Balcony Call Us

    Includes extra savings of up to £113pp

    more details

    Baja Peninsula, Mexican Riviera & Pacific Coast

    Holland America Line

    Zaandam 18 April 2026 18 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Catalina Island...

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £3,049pp
    • Ocean View £3,219pp
    • Balcony Call Us

    Includes extra savings of up to £214pp

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 25 April 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,599pp
    • Ocean View £1,679pp
    • Balcony Call Us

    Includes extra savings of up to £108pp

    more details

    Mexican Riviera & Pacific Coast

    Holland America Line

    Zaandam 25 April 2026 11 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Catalina Island - Vancouver

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,069pp
    • Ocean View £2,179pp
    • Balcony Call Us

    Includes extra savings of up to £141pp

    more details

    Pacific Coastal

    Holland America Line

    Koningsdam 27 April 2026 5 nights

    Itinerary: San Diego - San Francisco - Vancouver

    Cruise Only from

    • Interior £429pp
    • Ocean View £509pp
    • Balcony £589pp

    more details

    Grand World Voyage

    Holland America Line

    Volendam 03 May 2026 14 nights

    Itinerary: San Diego - Manzanillo - Puerto Chiapas - Acajutla - Panama City - Cartagena - Fort Lauderdale

    • Ask About Reduced Kids Places
    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Ask About FREE Cabin Upgrades
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,839pp
    • Ocean View £2,489pp
    • Balcony Call Us

    Includes extra savings of up to £214pp

    more details

    Panama Canal

    Holland America Line

    Nieuw Amsterdam 02 October 2026 16 nights

    Itinerary: San Diego - Puerto Vallarta - Huatalco - Puerto Chiapas - Puerto Quetzal - Acajutla - Cartagena - Half Moon Cay - Fort Lauderdale

    • Ask About Reduced Kids Places
    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,549pp
    • Ocean View £3,649pp
    • Balcony £3,649pp

    Includes extra savings of up to £224pp

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 08 October 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Ask About Reduced Kids Places
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £959pp
    • Ocean View £959pp
    • Balcony Call Us

    Includes extra savings of up to £77pp

    more details

    Panama Canal

    Holland America Line

    Eurodam 08 October 2026 16 nights

    Itinerary: San Diego - Cabo San Lucas - Acapulco - Huatalco - Puerto Chiapas - Puerto Quetzal - Puntarenas - Oranjestad - Fort Lauderdale

    • Ask About Reduced Kids Places
    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,499pp
    • Ocean View £3,559pp
    • Balcony £3,559pp

    Includes extra savings of up to £224pp

    more details

    Legendary Hawaii, Tahiti & Marquesas

    Holland America Line

    Zaandam 15 October 2026 35 nights

    Itinerary: San Diego - Nawiliwili - Honolulu - Kona - Kahului - Fanning Island - Rangiroa - Huahine - Bora Bora - Raiatea...

    • Ask About Reduced Kids Places
    • Ask About FREE Cabin Upgrades
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £5,479pp
    • Ocean View £5,479pp
    • Balcony Call Us

    Includes extra savings of up to £228pp

    more details

    Mexican Riviera & Sea of Cortez

    Holland America Line

    Koningsdam 20 October 2026 11 nights

    Itinerary: San Diego - Manzanillo - Puerto Vallarta - Mazatlan - La Paz - Loreto - Cabo San Lucas - San Diego

    • Ask About Reduced Kids Places
    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,509pp
    • Ocean View £2,049pp
    • Balcony £2,049pp

    Includes extra savings of up to £111pp

    more details

    Baja Peninsula

    Holland America Line

    Koningsdam 07 November 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Ask About Reduced Kids Places
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

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