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A cruise from San Diego is the perfect way to see the delights of the Mexican Riviera to the south or further up the Californian coast along the western seaboard all the way north to Vancouver, even as a one-way trip. Alternatively, there are also many itineraries departing for round-trip sailings to Hawaii. Typically with a duration of 7 to 10 days, whether you're a couple, family or solo traveller, and with plenty of flights options out of the UK to San Diego International Airport, you'll easily find the best cruise departing San Diego for you for 2026, 2027 and 2028 with Stewart Travel. Call one of our friendly Cruise Experts and book your dream San Diego cruise adventure today!
Luxury
Crystal Symphony 24 August 2026 12 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - Acajutla - San Juan del Sur - Puntarenas - Manta - Guayaquil
Cruise Only from
Luxury
Crystal Symphony 24 August 2026 32 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - Acajutla - San Juan del Sur - Puntarenas - Manta - Guayaquil - Panama Canal...
Cruise Only from
Nieuw Amsterdam 02 October 2026 16 nights
Itinerary: San Diego - Puerto Vallarta - Huatulco - Puerto Chiapas - Puerto Quetzal - Acajutla - Cartagena - Half Moon Cay - Fort Lauderdale
Cruise Only from
Includes extra savings of up to £194pp
Disney Wonder 03 October 2026 7 nights
Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Serenade of the Seas 04 October 2026 7 nights
Itinerary: San Diego - La Paz - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Zaandam 08 October 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego
Cruise Only from
Includes extra savings of up to £78pp
Eurodam 08 October 2026 16 nights
Itinerary: San Diego - Cabo San Lucas - Acapulco - Huatulco - Puerto Chiapas - Puerto Quetzal - Puntarenas - Oranjestad - Fort Lauderdale
Cruise Only from
Includes extra savings of up to £201pp
Zaandam 15 October 2026 35 nights
Itinerary: San Diego - Nawiliwili - Honolulu - Kahului - Kona - Fanning Island - Rangiroa - Huahine - Bora Bora - Raiatea...
Cruise Only from
Includes extra savings of up to £425pp
Serenade of the Seas 18 October 2026 7 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - La Paz - San Diego
Cruise Only from
Disney Magic 19 October 2026 5 nights
Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Koningsdam 20 October 2026 11 nights
Itinerary: San Diego - Manzanillo - Puerto Vallarta - Mazatlan - La Paz - Loreto - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £112pp
Disney Wonder 22 October 2026 5 nights
Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Disney Magic 24 October 2026 6 nights
Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Serenade of the Seas 25 October 2026 7 nights
Itinerary: San Diego - La Paz - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Disney Wonder 27 October 2026 6 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - San Diego
Cruise Only from
Disney Magic 30 October 2026 7 nights
Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Serenade of the Seas 01 November 2026 7 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - Mazatlan - San Diego
Cruise Only from
Includes extra savings of up to £22pp
Disney Magic 06 November 2026 14 nights
Itinerary: San Diego - Cabo San Lucas - Puerto Vallarta - Panama Canal - Cartagena - George Town - Galveston
Cruise Only from
Koningsdam 07 November 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego
Call us now on 0800 019 0063
Serenade of the Seas 08 November 2026 7 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - Mazatlan - San Diego
Cruise Only from
Includes extra savings of up to £21pp
Staff are very friendly and helpful and goes out of the way to find your perfect holiday.
Mr Dickson / April 2026
Second time we’ve used Stewart Travel. Great service, prompt response to enquiry and queries on both occasions. I’ve already recommended Stewart Travel to others based in our experience.
Mrs Hudson / April 2026
Very helpful, informative, friendly & welcoming
Trusted Customer / April 2026
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