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Cruises from San Diego, California

A cruise from San Diego is the perfect way to see the delights of the Mexican Riviera to the south or further up the Californian coast along the western seaboard all the way north to Vancouver, even as a one-way trip. Alternatively, there are also many itineraries departing for round-trip sailings to Hawaii. Typically with a duration of 7 to 10 days, whether you're a couple, family or solo traveller, and with plenty of flights options out of the UK to San Diego International Airport, you'll easily find the best cruise departing San Diego for you for 2026, 2027 and 2028 with Stewart Travel. Call one of our friendly Cruise Experts and book your dream San Diego cruise adventure today!

Cruises from San Diego

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    Mexican Riviera: Cabo & Puerto Vallarta

    Norwegian Cruise Line

    Norwegian Jade 04 April 2026 7 nights

    Itinerary: San Diego - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego

    • Includes Savings of up to 50%
    • Save up to £500 per couple off Flights - When Booking Balcony & Above Cabins
    • Upgrade for £249pp & get: Premium Drinks, Speciality Dining, WiFi & Excursion Discounts

    Cruise Only from

    • Interior £609pp
    • Ocean View Call Us
    • Balcony £1,359pp

    Includes extra savings of up to £42pp

    more details

    Pacific Coastal & Circle Hawaii Collector

    Holland America Line

    Nieuw Amsterdam 04 April 2026 25 nights

    Itinerary: San Diego - Catalina Island - San Francisco - Astoria - Britisch-Kolumbien - Vancouver - Kona - Kahalui - Honolulu - Nawiliwili...

    • FREE $400 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Wine Country & Pacific Northwest

    Holland America Line

    Nieuw Amsterdam 04 April 2026 7 nights

    Itinerary: San Diego - Catalina Island - San Francisco - Astoria - Britisch-Kolumbien - Vancouver

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera & Sea of Cortez

    Holland America Line

    Zaandam 07 April 2026 11 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - Mazatlan - Puerto Vallarta - Manzanillo - San Diego

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,149pp
    • Ocean View £2,259pp
    • Balcony Call Us

    Includes extra savings of up to £165pp

    more details

    Pacific Coast: San Francisco & Astoria

    Norwegian Cruise Line

    Norwegian Jade 11 April 2026 8 nights

    Itinerary: San Diego - San Francisco - Astoria - Seattle - Britisch-Kolumbien - Vancouver

    • Includes Savings of up to 50%
    • Save up to £500 per couple off Flights - When Booking Balcony & Above Cabins
    • Upgrade for £249pp & get: Premium Drinks, Speciality Dining, WiFi & Excursion Discounts

    Cruise Only from

    • Interior £589pp
    • Ocean View £629pp
    • Balcony £949pp

    more details

    Baja Peninsula

    Holland America Line

    Zaandam 18 April 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera & Baja Peninsula

    Holland America Line

    Zaandam 18 April 2026 14 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Baja Peninsula, Mexican Riviera & Pacific Coast

    Holland America Line

    Zaandam 18 April 2026 18 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Catalina Island...

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Wonder 24 April 2026 7 nights

    Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - Ensenada - San Diego

    Cruise Only from

    • Interior £1,299pp
    • Ocean View £1,499pp
    • Balcony £1,939pp

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 25 April 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,599pp
    • Ocean View £1,679pp
    • Balcony Call Us

    Includes extra savings of up to £108pp

    more details

    Mexican Riviera & Pacific Coast

    Holland America Line

    Zaandam 25 April 2026 11 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Catalina Island - Vancouver

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,069pp
    • Ocean View £2,179pp
    • Balcony Call Us

    Includes extra savings of up to £141pp

    more details

    Pacific Coastal

    Holland America Line

    Koningsdam 27 April 2026 5 nights

    Itinerary: San Diego - San Francisco - Vancouver

    Cruise Only from

    • Interior £429pp
    • Ocean View £509pp
    • Balcony £589pp

    more details

    Grand World Voyage

    Holland America Line

    Volendam 03 May 2026 14 nights

    Itinerary: San Diego - Manzanillo - Puerto Chiapas - Acajutla - Panama City - Cartagena - Fort Lauderdale

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,839pp
    • Ocean View £2,489pp
    • Balcony Call Us

    Includes extra savings of up to £214pp

    more details

    San Diego to Guayaquil

    Crystal Cruises

    Luxury

    Crystal Symphony 24 August 2026 12 nights

    Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - Acajutla - San Juan del Sur - Puntarenas - Manta - Guayaquil

    • FREE up to $500 On Board Spend per couple
    • Save up to £5000 per couple
    • Unlimited Beverages
    • Specialty Dining
    • Unlimited WiFi
    • Gratuities

    Cruise Only from

    • Ocean View £3,749pp
    • Balcony £4,559pp
    • Suite £4,919pp

    more details

    San Diego to New York City

    Crystal Cruises

    Luxury

    Crystal Symphony 24 August 2026 32 nights

    Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - Acajutla - San Juan del Sur - Puntarenas - Manta - Guayaquil - Panama Canal...

    • FREE up to $500 On Board Spend per couple
    • Save up to £5000 per couple
    • Unlimited Beverages
    • Specialty Dining
    • Unlimited WiFi
    • Gratuities

    Cruise Only from

    • Ocean View £10,269pp
    • Balcony £12,249pp
    • Suite £12,609pp

    more details

    Panama Canal

    Holland America Line

    Nieuw Amsterdam 02 October 2026 16 nights

    Itinerary: San Diego - Puerto Vallarta - Santa Cruz - Puerto Chiapas - Puerto Quetzal - Acajutla - Cartagena - Half Moon Cay - Fort Lauderdale

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,549pp
    • Ocean View £3,649pp
    • Balcony £3,649pp

    Includes extra savings of up to £224pp

    more details

    Halloween on the High Seas Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Wonder 03 October 2026 7 nights

    Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - Ensenada - San Diego

    Cruise Only from

    • Interior £1,219pp
    • Ocean View £1,449pp
    • Balcony £1,799pp

    more details

    Ensenada, Cabo & La Paz Cruise

    Royal Caribbean

    Serenade of the Seas 04 October 2026 7 nights

    Itinerary: San Diego - La Paz - Cabo San Lucas - Ensenada - San Diego

    • Ask About Reduced Kids Fares from £99pp

    Cruise Only from

    • Interior £509pp
    • Ocean View £589pp
    • Balcony £819pp

    Includes extra savings of up to £24pp

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 08 October 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • FREE up to $200 On Board Spend per couple - When Booking Have It All
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £959pp
    • Ocean View £959pp
    • Balcony Call Us

    Includes extra savings of up to £77pp

    more details

    Panama Canal

    Holland America Line

    Eurodam 08 October 2026 16 nights

    Itinerary: San Diego - Cabo San Lucas - Acapulco - Santa Cruz - Puerto Chiapas - Puerto Quetzal - Puntarenas - Oranjestad - Fort Lauderdale

    • FREE up to $300 On Board Spend per couple - When Booking Have It All
    • Ask About FREE Cabin Upgrades
    • Book Today from £99pp Deposit
    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,499pp
    • Ocean View £3,559pp
    • Balcony £3,559pp

    Includes extra savings of up to £224pp

    more details

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