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Cruises from San Diego, California

A cruise from San Diego is the perfect way to see the delights of the Mexican Riviera to the south or further up the Californian coast along the western seaboard all the way north to Vancouver, even as a one-way trip. Alternatively, there are also many itineraries departing for round-trip sailings to Hawaii. Typically with a duration of 7 to 10 days, whether you're a couple, family or solo traveller, and with plenty of flights options out of the UK to San Diego International Airport, you'll easily find the best cruise departing San Diego for you for 2026, 2027 and 2028 with Stewart Travel. Call one of our friendly Cruise Experts and book your dream San Diego cruise adventure today!

Cruises from San Diego

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    Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Wonder 24 April 2026 7 nights

    Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - Ensenada - San Diego

    Cruise Only from

    • Interior £1,319pp
    • Ocean View £1,529pp
    • Balcony £1,969pp

    more details

    Mexican Riviera & Pacific Coast

    Holland America Line

    Zaandam 25 April 2026 11 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego - Santa Catalina Island - Vancouver

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,069pp
    • Ocean View £2,179pp
    • Balcony Call Us

    Includes extra savings of up to £162pp

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 25 April 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Call us now on 0800 019 0063

    more details

    Pacific Coastal

    Holland America Line

    Koningsdam 27 April 2026 5 nights

    Itinerary: San Diego - San Francisco - Vancouver

    • Ask About FREE up to $400 On Board Spend per couple - When Booking Have It All

    Cruise Only from

    • Interior £429pp
    • Ocean View £509pp
    • Balcony £589pp

    more details

    Grand World Voyage

    Holland America Line

    Volendam 03 May 2026 14 nights

    Itinerary: San Diego - Manzanillo - Puerto Chiapas - Acajutla - Panama City - Cartagena - Fort Lauderdale

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,839pp
    • Ocean View £2,489pp
    • Balcony Call Us

    Includes extra savings of up to £214pp

    more details

    San Diego to Guayaquil

    Crystal Cruises

    Luxury

    Crystal Symphony 24 August 2026 12 nights

    Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - Acajutla - San Juan del Sur - Puntarenas - Manta - Guayaquil

    • Save up to 30%
    • Unlimited Beverages
    • Specialty Dining
    • Unlimited WiFi
    • Gratuities

    Cruise Only from

    • Ocean View £3,659pp
    • Balcony £5,009pp
    • Suite £5,289pp

    more details

    San Diego to New York City

    Crystal Cruises

    Luxury

    Crystal Symphony 24 August 2026 32 nights

    Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - Acajutla - San Juan del Sur - Puntarenas - Manta - Guayaquil - Panama Canal...

    • Save up to 30%
    • Unlimited Beverages
    • Specialty Dining
    • Unlimited WiFi
    • Gratuities

    Cruise Only from

    • Ocean View £10,159pp
    • Balcony £13,599pp
    • Suite £13,969pp

    more details

    Panama Canal

    Holland America Line

    Nieuw Amsterdam 02 October 2026 16 nights

    Itinerary: San Diego - Puerto Vallarta - Huatulco - Puerto Chiapas - Puerto Quetzal - Acajutla - Cartagena - Half Moon Cay - Fort Lauderdale

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,269pp
    • Ocean View £2,339pp
    • Balcony £3,099pp

    Includes extra savings of up to £194pp

    more details

    Halloween on the High Seas Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Wonder 03 October 2026 7 nights

    Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - Ensenada - San Diego

    Cruise Only from

    • Interior £1,289pp
    • Ocean View £1,479pp
    • Balcony £1,829pp

    more details

    7 Night Ensenada, Cabo & La Paz Cruise

    Royal Caribbean

    Serenade of the Seas 04 October 2026 7 nights

    Itinerary: San Diego - La Paz - Cabo San Lucas - Ensenada - San Diego

    • Limited Time Savings - Call Our Cruise Experts Today
    • Big Balcony Sale - Upgrade for Less

    Cruise Only from

    • Interior £459pp
    • Ocean View £549pp
    • Balcony £649pp

    Includes extra savings of up to £24pp

    more details

    Mexican Riviera

    Holland America Line

    Zaandam 08 October 2026 7 nights

    Itinerary: San Diego - Cabo San Lucas - La Paz - Loreto - San Diego

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £999pp
    • Ocean View £1,029pp
    • Balcony Call Us

    Includes extra savings of up to £78pp

    more details

    Panama Canal

    Holland America Line

    Eurodam 08 October 2026 16 nights

    Itinerary: San Diego - Cabo San Lucas - Acapulco - Huatulco - Puerto Chiapas - Puerto Quetzal - Puntarenas - Oranjestad - Fort Lauderdale

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £2,329pp
    • Ocean View £2,389pp
    • Balcony £3,129pp

    Includes extra savings of up to £201pp

    more details

    Legendary Hawaii, Tahiti & Marquesas

    Holland America Line

    Zaandam 15 October 2026 35 nights

    Itinerary: San Diego - Nawiliwili - Honolulu - Kona - Kahului - Fanning Island - Rangiroa - Huahine - Bora Bora - Raiatea...

    Cruise Only from

    • Interior Call Us
    • Ocean View £5,649pp
    • Balcony Call Us

    Includes extra savings of up to £438pp

    more details

    7 Night Ensenada, Cabo & La Paz Cruise

    Royal Caribbean

    Serenade of the Seas 18 October 2026 7 nights

    Itinerary: San Diego - Ensenada - Cabo San Lucas - La Paz - San Diego

    • Limited Time Savings - Call Our Cruise Experts Today
    • Big Balcony Sale - Upgrade for Less

    Cruise Only from

    • Interior £469pp
    • Ocean View £539pp
    • Balcony £649pp

    Includes extra savings of up to £24pp

    more details

    Halloween on the High Seas Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Magic 19 October 2026 5 nights

    Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego

    Cruise Only from

    • Interior £899pp
    • Ocean View £1,039pp
    • Balcony £1,289pp

    more details

    Mexican Riviera & Sea of Cortez

    Holland America Line

    Koningsdam 20 October 2026 11 nights

    Itinerary: San Diego - Manzanillo - Puerto Vallarta - Mazatlan - La Paz - Loreto - Cabo San Lucas - San Diego

    • Have It All - Beverage Package, Speciality Dining, Shore Excursion Credit, WiFi, Gratuities

    Cruise Only from

    • Interior £1,479pp
    • Ocean View £1,599pp
    • Balcony £1,909pp

    Includes extra savings of up to £112pp

    more details

    Halloween on the High Seas Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Wonder 22 October 2026 5 nights

    Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego

    Cruise Only from

    • Interior £869pp
    • Ocean View £1,019pp
    • Balcony £1,229pp

    more details

    Halloween on the High Seas Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Magic 24 October 2026 6 nights

    Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego

    Cruise Only from

    • Interior £919pp
    • Ocean View £1,089pp
    • Balcony £1,359pp

    more details

    7 Night Ensenada, Cabo & La Paz Cruise

    Royal Caribbean

    Serenade of the Seas 25 October 2026 7 nights

    Itinerary: San Diego - La Paz - Cabo San Lucas - Ensenada - San Diego

    • Limited Time Savings - Call Our Cruise Experts Today
    • Big Balcony Sale - Upgrade for Less

    Cruise Only from

    • Interior £469pp
    • Ocean View £529pp
    • Balcony £579pp

    Includes extra savings of up to £20pp

    more details

    Halloween on the High Seas Mexican Riviera Cruise from San Diego

    Disney Cruise Line

    Disney Wonder 27 October 2026 6 nights

    Itinerary: San Diego - Ensenada - Cabo San Lucas - San Diego

    Cruise Only from

    • Interior £1,009pp
    • Ocean View £1,199pp
    • Balcony £1,499pp

    more details

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