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Cruises from Southampton to Italy

Find the best cruise to Italy from Southampton for you in 2026, 2027 and 2028 with Stewart Travel below. Call one of our Cruise Experts on 0800 019 0063 to book your dream cruise holiday today!

Italian Cruises from Southampton

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    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 07 June 2026 14 nights

    Itinerary: Southampton - Seville - Barcelona - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,329pp
    • Ocean View £1,779pp
    • Balcony £1,929pp

    Includes extra savings of up to £19pp

    more details

    Mediterranean And Morocco Discovery

    P&O Cruises

    Arcadia 10 June 2026 19 nights

    Itinerary: Southampton - Lisbon - Alicante - Florence/Pisa - Rome - Cartagena - Casablanca - Tangier - Vigo - Southampton

    • Adult Only
    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    • Interior £2,179pp
    • Ocean View Call Us
    • Balcony Call Us

    Includes extra savings of up to £22pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 05 July 2026 14 nights

    Itinerary: Southampton - Seville - Barcelona - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,179pp
    • Ocean View £1,729pp
    • Balcony £1,829pp

    Includes extra savings of up to £28pp

    more details

    Norwegian Fjords & Mediterranean Adventurer

    Princess Cruises

    Sky Princess 11 July 2026 21 nights

    Itinerary: Southampton - Bergen - Skjolden - Olden - Stavanger - Southampton - Seville - Barcelona - Toulon - Florence/Pisa...

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities

    Sail From UK from

    • Interior £2,609pp
    • Ocean View Call Us
    • Balcony £3,679pp
    • Suite £4,339pp

    Includes extra savings of up to £134pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 18 July 2026 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Corsica - Southampton

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,559pp
    • Ocean View Call Us
    • Balcony £1,839pp
    • Suite £2,449pp

    Includes extra savings of up to £76pp

    more details

    London to Istanbul

    Oceania Cruises

    Luxury

    Sirena 05 August 2026 22 nights

    Itinerary: Southampton - Bordeaux - Biarritz - Santander - Ferrol - Porto - Lisbon - Seville - Malaga - Almeria...

    • Includes Savings of up to 50%
    • Gratuities
    • Gourmet Speciality Dining
    • Soft Drinks, Bottled Water, Speciality Tea & Coffee
    • Unlimited WiFi
    • In Suite & In Stateroom Dining

    Sail From UK from

    • Interior £5,209pp
    • Ocean View £5,459pp
    • Balcony £8,759pp
    • Suite £10,989pp

    Includes extra savings of up to £578pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 30 August 2026 14 nights

    Itinerary: Southampton - Seville - Barcelona - La Seyne-sur-Mer - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    Italy, France And Spain

    Cunard

    Queen Anne 06 September 2026 14 nights

    Itinerary: Southampton - Cartagena - Rome - Florence/Pisa - Marseille - Malaga - Gibraltar - Southampton

    • FREE up to $1000 On Board Spend - When Booking Cunard Fare
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £1,679pp
    • Ocean View Call Us
    • Balcony £3,499pp
    • Suite £5,639pp

    more details

    Spain And Italy

    Cunard

    Queen Anne 06 September 2026 6 nights

    Itinerary: Southampton - Cartagena - Rome

    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    14 Night Best Of Italy, Spain & France

    Celebrity Cruises

    Luxury

    Celebrity Apex 12 September 2026 14 nights

    Itinerary: Southampton - Cadiz - Cagliari - Rome - Florence/Pisa - Nice (Villefranche) - Barcelona - La Coruna - Southampton

    • Ask about adding Drinks & WiFi

    Sail From UK from

    • Interior £2,759pp
    • Ocean View £2,979pp
    • Balcony £3,259pp
    • Suite £20,309pp

    more details

    Central Mediterranean Discovery

    P&O Cruises

    Ventura 26 February 2027 21 nights

    Itinerary: Southampton - Cartagena - La Goulette - Malta - Athens - Naples - Rome - Barcelona - Alicante - Cadiz...

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    • Interior £1,659pp
    • Ocean View £1,779pp
    • Balcony £2,249pp

    Includes extra savings of up to £49pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 29 March 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Corsica - Southampton

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities
    • Ask About FREE up to $1000 On Board Spend
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,359pp
    • Ocean View £1,619pp
    • Balcony £1,539pp
    • Suite £1,859pp

    Includes extra savings of up to £58pp

    more details

    Culture & Coastline of Italy

    Fred Olsen Cruise Lines

    Small Ship Experience

    Balmoral 02 April 2027 18 nights

    Itinerary: Southampton - Cadiz - Florence/Pisa - Rome - Olbia/Sardinia - Alghero - Mahon - Southampton

    • Wine, Beer & Soft Drinks Included with Lunch & Dinner - When Booking Freedom Fare
    • Gratuities Included
    • Upgrade to Premium Drinks from £40pp per day
    • Features Fred. Olsen Signature Experiences - Scenic Discoveries, Itinerary Insights & Destination Inspired Menus

    Sail From UK from

    • Interior £2,249pp
    • Ocean View £2,839pp
    • Balcony £4,989pp

    Includes extra savings of up to £112pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 25 April 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    Mediterranean and Greek Islands

    Cunard

    Queen Elizabeth 02 May 2027 26 nights

    Itinerary: Southampton - La Coruna - Leixoes - Tangier - Gibraltar - Cartagena - Alicante - Valencia - Barcelona - Sicily...

    • FREE up to $1000 On Board Spend - When Booking Cunard Fare
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £2,979pp
    • Ocean View £3,179pp
    • Balcony £3,569pp
    • Suite £7,249pp

    Includes extra savings of up to £148pp

    more details

    Mediterranean, Greek Islands and Adriatic

    Cunard

    Queen Elizabeth 02 May 2027 33 nights

    Itinerary: Southampton - La Coruna - Leixoes - Tangier - Gibraltar - Cartagena - Alicante - Valencia - Barcelona - Sicily...

    • FREE up to $1000 On Board Spend - When Booking Cunard Fare
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £3,669pp
    • Ocean View £3,919pp
    • Balcony £4,599pp
    • Suite £9,799pp

    Includes extra savings of up to £200pp

    more details

    Mediterranean, Greek Islands and Adriatic

    Cunard

    Queen Elizabeth 02 May 2027 40 nights

    Itinerary: Southampton - La Coruna - Leixoes - Tangier - Gibraltar - Cartagena - Alicante - Valencia - Barcelona - Sicily...

    • FREE up to $1000 On Board Spend - When Booking Cunard Fare
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £4,409pp
    • Ocean View £4,699pp
    • Balcony £5,779pp
    • Suite £11,069pp

    Includes extra savings of up to £226pp

    more details

    Spain and Portugal

    Cunard

    Queen Victoria 04 May 2027 24 nights

    Itinerary: Southampton - Lisbon - Cadiz - Alicante - Valencia - Majorca - Barcelona - Athens - Istanbul - Kusadasi...

    • FREE up to $1000 On Board Spend - When Booking Cunard Fare
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    Call us now on 0800 019 0063

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 09 May 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    • Interior £1,279pp
    • Ocean View £1,909pp
    • Balcony £2,139pp

    Includes extra savings of up to £31pp

    more details

    Italy, Spain and Portugal

    Cunard

    Queen Anne 09 May 2027 18 nights

    Itinerary: Southampton - Lisbon - Alicante - Barcelona - Rome - Naples - Sicily - Cagliari - Malaga - Cadiz...

    • FREE up to $1000 On Board Spend - When Booking Cunard Fare
    • Upgrade to Include Beverage Collection, WiFi & Dining Credit from £60pp per day
    • Elevate your Experience - Upgrade to Grill Suites - Ask for full details

    Sail From UK from

    • Interior £1,509pp
    • Ocean View £1,999pp
    • Balcony £2,449pp
    • Suite £5,749pp

    Includes extra savings of up to £117pp

    more details

    London to Stockholm

    Oceania Cruises

    Luxury

    Insignia 27 May 2027 14 nights

    Itinerary: Southampton - Zeebrugge - Amsterdam - Kiel - Warnemunde (For Berlin) - Szczecin - Rome - Klaipeda - Visby - Riga...

    • Includes Savings of up to 50%
    • Gratuities
    • Gourmet Speciality Dining
    • Soft Drinks, Bottled Water, Speciality Tea & Coffee
    • Unlimited WiFi
    • In Suite & In Stateroom Dining

    Sail From UK from

    • Interior £3,479pp
    • Ocean View £3,729pp
    • Balcony £4,779pp
    • Suite £6,759pp

    Includes extra savings of up to £356pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 06 June 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required

    Sail From UK from

    • Interior £1,429pp
    • Ocean View £1,879pp
    • Balcony £2,269pp

    Includes extra savings of up to £30pp

    more details

    Mediterranean - Spain France And Italy

    P&O Cruises

    Arvia 04 July 2027 14 nights

    Itinerary: Southampton - Cadiz - Barcelona - Toulon - Florence/Pisa - Rome - Alicante - Southampton

    • Upgrade to the new P&O All-Inclusive Package - Drinks, Wi-Fi & Dining Credit from only £49pp per day
    • FREE Extra On Board Spend When Booking Select Fare Pricing
    • No Tipping Required
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,379pp
    • Ocean View £1,929pp
    • Balcony £2,019pp

    Includes extra savings of up to £29pp

    more details

    London (Southampton) to Athens (Piraeus)

    Regent Seven Seas Cruises

    Luxury

    Seven Seas Mariner 30 July 2027 82 nights

    Itinerary: Southampton - Honfleur - St. Peter Port - St Malo - La Rochelle - Bordeaux - Biarritz - Bilbao - Santiago de Compostela - Lisbon...

    • Unlimited Beverages
    • Gratuities
    • Unlimited Shore Excursions

    Sail From UK from

    • Suite £50,619pp

    Includes extra savings of up to £2,664pp

    more details

    Mediterranean Adventurer

    Princess Cruises

    Sky Princess 07 August 2027 14 nights

    Itinerary: Southampton - Seville - Barcelona - Toulon - Florence/Pisa - Rome - Alghero - Southampton

    • Upgrade for only £50pp per day & get: All Inclusive Drinks, WiFi, Four Casual Dining Meals & Gratuities
    • Ask About FREE up to $1000 On Board Spend
    • Big Balcony Sale - Upgrade for Less

    Sail From UK from

    • Interior £1,309pp
    • Ocean View £1,699pp
    • Balcony £1,619pp
    • Suite £1,949pp

    Includes extra savings of up to £60pp

    more details

    • Next

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